Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   M3B_RS04340 Genome accession   NZ_AP014596
Coordinates   789093..790055 (+) Length   320 a.a.
NCBI ID   WP_011054653.1    Uniprot ID   A0A0H2UV79
Organism   Streptococcus pyogenes strain M3-b     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 784093..795055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3B_RS04315 (M3B_0878) - 784096..784686 (+) 591 WP_002983984.1 serine hydrolase -
  M3B_RS04320 (M3B_0879) - 784800..786020 (-) 1221 WP_011054655.1 DUF3114 domain-containing protein -
  M3B_RS04325 (M3B_0880) queA 786027..787055 (-) 1029 WP_002995782.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  M3B_RS04330 (M3B_0881) nagB 787257..787961 (+) 705 WP_002995779.1 glucosamine-6-phosphate deaminase -
  M3B_RS04335 (M3B_0882) - 788080..788796 (+) 717 WP_011106718.1 pseudouridine synthase -
  M3B_RS04340 (M3B_0883) coiA 789093..790055 (+) 963 WP_011054653.1 competence protein CoiA Machinery gene
  M3B_RS04345 (M3B_0884) pepF 790068..791873 (+) 1806 WP_011054652.1 oligoendopeptidase F Regulator
  M3B_RS04350 (M3B_0885) - 792249..793445 (+) 1197 WP_011054651.1 OFA family MFS transporter -
  M3B_RS04355 (M3B_0886) - 793510..794217 (+) 708 WP_002984000.1 O-methyltransferase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37824.21 Da        Isoelectric Point: 10.2092

>NTDB_id=55662 M3B_RS04340 WP_011054653.1 789093..790055(+) (coiA) [Streptococcus pyogenes strain M3-b]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRSHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWMNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIEGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=55662 M3B_RS04340 WP_011054653.1 789093..790055(+) (coiA) [Streptococcus pyogenes strain M3-b]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGATCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGATGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTGAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV79

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.024

100

0.4

Multiple sequence alignment