Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   SMUNUM_RS09335 Genome accession   NZ_AP014571
Coordinates   1884376..1885407 (-) Length   343 a.a.
NCBI ID   WP_255262721.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1879376..1890407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS09295 tnpA 1879676..1880139 (-) 464 Protein_1786 IS200/IS605 family transposase -
  SMUNUM_RS09300 (SMNUM_1767) - 1880352..1881551 (-) 1200 WP_002263443.1 acetate kinase -
  SMUNUM_RS09305 (SMNUM_1768) comGH 1881610..1882563 (-) 954 WP_019805509.1 class I SAM-dependent methyltransferase Machinery gene
  SMUNUM_RS09310 (SMNUM_1769) comGG 1882618..1883007 (-) 390 WP_019805510.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUNUM_RS09315 (SMNUM_1770) comGF 1882985..1883419 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUNUM_RS09320 (SMNUM_1771) comGE 1883406..1883699 (-) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUNUM_RS09325 (SMNUM_1772) comGD 1883671..1884075 (-) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUNUM_RS09330 (SMNUM_1773) comGC 1884062..1884376 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUNUM_RS09335 (SMNUM_1774) comGB 1884376..1885407 (-) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUNUM_RS09340 (SMNUM_1775) comGA 1885343..1886284 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUNUM_RS09345 (SMNUM_1776) - 1886414..1886797 (-) 384 WP_019805511.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39844.46 Da        Isoelectric Point: 9.5151

>NTDB_id=55593 SMUNUM_RS09335 WP_255262721.1 1884376..1885407(-) (comGB) [Streptococcus mutans LP13]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=55593 SMUNUM_RS09335 WP_255262721.1 1884376..1885407(-) (comGB) [Streptococcus mutans LP13]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA159

100

100

1
  comGB Streptococcus mutans UA140

99.417

100

0.994
  comGB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment