Detailed information NTG0055502

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SMUNUM_RS01525
• Genome accession: NZ_AP014571
• Coordinates: 295349..296245 (+)
• Length: 298 a.a.
• NCBI ID: WP_002282762.1
• Uniprot ID: -
• Organism: Streptococcus mutans LP13
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 290349..301245

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNUM_RS01495 (SMNUM_0257)	-	291202..291765 (+)	564	WP_002262916.1	nucleotidyltransferase family protein	-
SMUNUM_RS01500 (SMNUM_0258)	-	292192..293205 (+)	1014	WP_002262915.1	YdcF family protein	-
SMUNUM_RS01505 (SMNUM_0259)	-	293282..294058 (+)	777	WP_002351835.1	MBL fold metallo-hydrolase	-
SMUNUM_RS01510 (SMNUM_0260)	tadA	294058..294528 (+)	471	WP_002266500.1	tRNA adenosine(34) deaminase TadA	-
SMUNUM_RS01515 (SMNUM_0261)	-	294525..295088 (+)	564	WP_002262912.1	hypothetical protein	-
SMUNUM_RS01525 (SMNUM_0262)	comR	295349..296245 (+)	897	WP_002282762.1	XRE family transcriptional regulator	Regulator
SMUNUM_RS01530 (SMNUM_0263)	-	297020..297769 (+)	750	WP_002282760.1	hypothetical protein	-
SMUNUM_RS01535 (SMNUM_0264)	-	297780..298358 (+)	579	WP_002282759.1	CPBP family intramembrane glutamic endopeptidase	-
SMUNUM_RS01540 (SMNUM_0265)	-	298368..298796 (+)	429	WP_002272213.1	Msa family membrane protein	-
SMUNUM_RS01545 (SMNUM_0266)	-	298789..299655 (+)	867	WP_002272214.1	ABC transporter ATP-binding protein	-
SMUNUM_RS01550 (SMNUM_0267)	-	299658..300407 (+)	750	WP_002272215.1	hypothetical protein	-

Sequence

Protein

• Length: 298 a.a.
• Molecular weight: 34760.54 Da
• Isoelectric Point: 4.4449

>NTDB_id=55502 SMUNUM_RS01525 WP_002282762.1 295349..296245(+) (comR) [Streptococcus mutans LP13]
MSVKETIGQKIREEREKKGLSREQLCDTEEELTARQLVRIELGQSLPSIVKLEFIAKKLETDLTTLLAGESITIPEEYFT
MKYQLFKFPTYGDPKRLEQKTQMIEDIYEKYFDVLPEEELFTLELLDNSLDYISTGKTEAAEFIFEDFFKQLLIKKHYSF
NDLLLAKYYAIQYQNKDYKETIMETLETAILQQSVSGDEYYNIELLGALTAIAGVYLDHAEYSKLKNLVDRMHEVIEETQ
QHSAKPIVLIYEAKYYLYSEQNKEKAKGCYDLAALLAQNFGDDVLETNIEAERKKDQV

Nucleotide

• Length: 897 bp

>NTDB_id=55502 SMUNUM_RS01525 WP_002282762.1 295349..296245(+) (comR) [Streptococcus mutans LP13]
ATGAGTGTAAAGGAAACGATTGGTCAGAAAATTAGGGAAGAAAGAGAAAAAAAGGGTCTGTCACGTGAACAACTATGTGA
TACTGAAGAAGAATTAACGGCTCGTCAACTGGTACGTATTGAACTGGGGCAATCTTTACCGTCTATTGTAAAGCTGGAGT
TTATTGCAAAAAAATTGGAGACTGATTTAACCACTTTACTTGCAGGTGAAAGTATTACCATTCCAGAAGAATATTTCACT
ATGAAGTATCAGCTTTTCAAATTTCCCACTTATGGGGATCCTAAGCGTCTGGAACAGAAAACGCAAATGATTGAAGATAT
TTATGAAAAGTACTTTGATGTTTTGCCGGAGGAGGAGCTTTTTACTTTGGAATTACTGGATAACTCTTTAGATTATATCT
CCACAGGAAAAACAGAAGCAGCTGAATTTATCTTTGAAGATTTTTTTAAACAACTTTTAATAAAAAAGCATTATTCTTTC
AATGACCTGTTATTAGCAAAATACTATGCGATTCAATATCAAAATAAAGATTATAAAGAAACAATCATGGAGACCCTCGA
AACTGCTATTTTACAACAAAGTGTCTCAGGTGATGAATACTATAATATTGAACTTTTAGGGGCATTGACGGCTATAGCAG
GCGTTTATCTGGATCATGCTGAGTATTCTAAATTAAAAAATTTAGTAGATAGAATGCATGAAGTGATTGAGGAGACACAG
CAGCACAGTGCTAAGCCTATAGTATTAATTTATGAGGCTAAATACTATCTCTATAGTGAACAAAACAAGGAGAAAGCAAA
AGGATGCTATGATTTAGCTGCTTTGCTGGCTCAGAATTTTGGTGATGATGTCTTAGAGACAAACATTGAAGCTGAAAGAA
AAAAAGATCAGGTATAG

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (75-292)

• Helix-turn-helix domain (HTH_19) (8-70)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	43.771	99.664	0.436
comR	Streptococcus thermophilus LMD-9	43.771	99.664	0.436
comR	Streptococcus salivarius SK126	43.771	99.664	0.436
comR	Streptococcus salivarius strain HSISS4	43.434	99.664	0.433
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.416
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	39.465	100	0.396