Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   LXA49_RS00215 Genome accession   NZ_CP089949
Coordinates   35349..35585 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain SN75752     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 30349..40585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS00205 (LXA49_00200) - 33978..34187 (+) 210 Protein_34 transposase -
  LXA49_RS00210 (LXA49_00205) - 34222..35083 (-) 862 Protein_35 transposase -
  LXA49_RS00215 (LXA49_00210) comW 35349..35585 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  LXA49_RS00220 (LXA49_00215) - 35816..37102 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  LXA49_RS00225 (LXA49_00220) - 37366..38514 (-) 1149 WP_000876726.1 site-specific integrase -
  LXA49_RS00230 (LXA49_00225) - 38693..39616 (-) 924 WP_000122590.1 exonuclease domain-containing protein -
  LXA49_RS00235 (LXA49_00230) - 39629..40012 (-) 384 WP_000136455.1 ImmA/IrrE family metallo-endopeptidase -
  LXA49_RS00240 (LXA49_00235) - 40025..40387 (-) 363 WP_000466344.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=552755 LXA49_RS00215 WP_000939545.1 35349..35585(+) (comW) [Streptococcus pneumoniae strain SN75752]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=552755 LXA49_RS00215 WP_000939545.1 35349..35585(+) (comW) [Streptococcus pneumoniae strain SN75752]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744