Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   J7T92_RS01735 Genome accession   NZ_CP072429
Coordinates   316767..317456 (+) Length   229 a.a.
NCBI ID   WP_002949638.1    Uniprot ID   A0A060BFD8
Organism   Streptococcus thermophilus strain S24747     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 311767..322456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T92_RS01710 - 312733..312903 (+) 171 Protein_284 ascorbate 6-phosphate lactonase -
  J7T92_RS01715 (J7T92_01730) - 312920..313591 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  J7T92_RS01720 (J7T92_01735) - 313631..314995 (-) 1365 WP_372588804.1 TrkH family potassium uptake protein -
  J7T92_RS01725 (J7T92_01740) rsmG 315065..315778 (-) 714 WP_138496718.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  J7T92_RS01730 (J7T92_01745) - 316075..316611 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  J7T92_RS01735 (J7T92_01750) covR 316767..317456 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  J7T92_RS01740 (J7T92_01755) covS 317453..318970 (+) 1518 WP_014607970.1 HAMP domain-containing histidine kinase Regulator
  J7T92_RS01745 (J7T92_01760) nrdR 319092..319571 (+) 480 WP_011680738.1 transcriptional regulator NrdR -
  J7T92_RS01750 (J7T92_01765) - 319568..320743 (+) 1176 WP_372588803.1 DnaD domain protein -
  J7T92_RS01755 (J7T92_01770) dnaI 320747..321649 (+) 903 WP_014607971.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26655.77 Da        Isoelectric Point: 4.7059

>NTDB_id=552624 J7T92_RS01735 WP_002949638.1 316767..317456(+) (covR) [Streptococcus thermophilus strain S24747]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=552624 J7T92_RS01735 WP_002949638.1 316767..317456(+) (covR) [Streptococcus thermophilus strain S24747]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTTCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAGACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BFD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.07

100

0.961
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441