Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   J7U22_RS03620 Genome accession   NZ_CP072428
Coordinates   705496..706836 (+) Length   446 a.a.
NCBI ID   WP_372588877.1    Uniprot ID   A0A3G6JJJ9
Organism   Streptococcus thermophilus strain S24749     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 700496..711836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS03595 (J7U22_03585) - 701279..701929 (-) 651 WP_011226088.1 amino acid ABC transporter permease -
  J7U22_RS03600 (J7U22_03590) - 701941..702639 (-) 699 WP_011681209.1 amino acid ABC transporter permease -
  J7U22_RS03605 (J7U22_03595) - 702657..703490 (-) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  J7U22_RS03610 (J7U22_03600) - 703502..704269 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  J7U22_RS03615 (J7U22_03605) vicR 704796..705503 (+) 708 WP_011681206.1 response regulator YycF Regulator
  J7U22_RS03620 (J7U22_03610) vicK 705496..706836 (+) 1341 WP_372588877.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J7U22_RS03625 (J7U22_03615) vicX 706842..707654 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  J7U22_RS03630 (J7U22_03620) - 707714..708075 (+) 362 Protein_693 YbaN family protein -
  J7U22_RS03635 (J7U22_03625) - 708127..709341 (-) 1215 WP_002953123.1 aminoacyltransferase -
  J7U22_RS03640 (J7U22_03630) yidA 709343..710152 (-) 810 WP_011226081.1 sugar-phosphatase -
  J7U22_RS03645 (J7U22_03635) - 710360..711238 (+) 879 Protein_696 GNAT family N-acetyltransferase -
  J7U22_RS03650 (J7U22_03640) - 711330..711716 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50738.03 Da        Isoelectric Point: 5.2464

>NTDB_id=552572 J7U22_RS03620 WP_372588877.1 705496..706836(+) (vicK) [Streptococcus thermophilus strain S24749]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALICKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=552572 J7U22_RS03620 WP_372588877.1 705496..706836(+) (vicK) [Streptococcus thermophilus strain S24749]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTTGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)

PAS fold (PAS)

(94-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G6JJJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92.825

0.688
  micB Streptococcus pneumoniae Cp1015

65.82

97.085

0.639