Detailed information NTG0552236

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: J5A60_RS01150
• Genome accession: NZ_CP072381
• Coordinates: 210218..211642 (-)
• Length: 474 a.a.
• NCBI ID: WP_212510296.1
• Uniprot ID: -
• Organism: Aggregatibacter sp. oral taxon 513 strain W11186
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 205218..216642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5A60_RS01130 (J5A60_01130)	-	206134..206505 (-)	372	WP_212510293.1	hypothetical protein	-
J5A60_RS01135 (J5A60_01135)	-	206813..207391 (+)	579	WP_212510294.1	NAD(P)H-dependent oxidoreductase	-
J5A60_RS01140 (J5A60_01140)	-	207483..208349 (-)	867	WP_212510295.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
J5A60_RS01145 (J5A60_01145)	aroB	208354..209442 (-)	1089	WP_249113880.1	3-dehydroquinate synthase	-
J5A60_RS09510	aroK	209476..210003 (-)	528	WP_048750075.1	shikimate kinase AroK	-
J5A60_RS01150 (J5A60_01150)	comE	210218..211642 (-)	1425	WP_212510296.1	type IV pilus secretin PilQ	Machinery gene
J5A60_RS01155 (J5A60_01155)	-	211662..212048 (-)	387	WP_212510297.1	pilus assembly protein PilP	-
J5A60_RS01160 (J5A60_01160)	-	212059..212586 (-)	528	WP_212510298.1	competence protein	-
J5A60_RS01165 (J5A60_01165)	-	212583..213101 (-)	519	WP_212510299.1	PilN domain-containing protein	-
J5A60_RS01170 (J5A60_01170)	-	213098..213919 (-)	822	WP_212510300.1	competence protein ComA	-
J5A60_RS01175 (J5A60_01175)	-	214030..216597 (+)	2568	WP_212510301.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 474 a.a.
• Molecular weight: 52154.86 Da
• Isoelectric Point: 7.2654

>NTDB_id=552236 J5A60_RS01150 WP_212510296.1 210218..211642(-) (comE) [Aggregatibacter sp. oral taxon 513 strain W11186]
MQSLFLKILKCGLFFGCFFTFAVHAEQHQTFSIQLKQAPLVPTLQQLALAQNVNSLIDDELQGTLTLKLDNVDLDQLFHS
VAKIKQLDLWQEDGIYYLSKRDTAAKFAGNITEPQPIASLPPEEDTSLATATIKLHFAKASDVMKSLTGGNGSMLSPNGS
ITFDDRSNLLLIQDEPKSIANLKKLIKELDKPIEQIAIEARIVTINAESLKELGVRWGIFNPTENAHKIAGSLAANGFDN
IANQLNVNLPTATTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYIMVNEKSGTQ
SVEFREAVLGLEVTPHISLDKQILLDLIVSQNAPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFHDTVTKSLD
KVPLLGDIPGIKHLFSKESDRHQKRELVIFVTPHILRQGETLENLKNNQSTAKKNKKQEKSKTAQNKPKKERNP

Nucleotide

• Length: 1425 bp

>NTDB_id=552236 J5A60_RS01150 WP_212510296.1 210218..211642(-) (comE) [Aggregatibacter sp. oral taxon 513 strain W11186]
ATGCAATCGCTTTTTCTCAAGATCTTAAAGTGCGGTCTGTTTTTCGGATGTTTTTTCACGTTCGCCGTGCATGCCGAACA
ACATCAAACCTTTTCCATTCAACTCAAACAGGCACCTTTAGTGCCGACCTTACAACAACTTGCGCTGGCTCAAAATGTTA
ACTCGCTGATTGACGACGAATTACAAGGCACACTGACATTAAAGTTAGATAACGTAGATTTAGATCAGCTCTTTCATTCC
GTTGCCAAAATCAAACAATTAGATTTATGGCAGGAAGACGGCATTTATTATTTAAGTAAACGTGATACCGCCGCCAAATT
TGCCGGCAATATCACAGAACCTCAACCCATTGCATCACTCCCCCCTGAGGAAGACACCTCGCTCGCGACTGCCACCATTA
AACTGCACTTTGCCAAAGCCTCTGACGTCATGAAATCGCTTACCGGCGGTAACGGGTCGATGTTATCGCCGAATGGCAGC
ATTACCTTTGATGACCGCAGCAATCTCTTGCTGATTCAAGACGAACCAAAATCCATCGCCAATTTGAAAAAATTGATTAA
GGAATTGGATAAGCCCATTGAACAAATTGCCATAGAAGCACGTATCGTCACCATCAACGCGGAAAGTTTGAAAGAATTAG
GTGTCCGTTGGGGAATTTTCAACCCGACAGAAAATGCCCACAAAATCGCTGGCAGTCTCGCCGCTAACGGCTTTGACAAT
ATTGCGAATCAATTAAACGTGAACCTGCCGACTGCCACGACACCGGCGGGGTCTCTCGCGTTACAAGTCGCCAAAATCAA
CGGACGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAACAATGTGGAGATTATCGCCAGTCCTCGTTTACTCA
CCACGAACAAGAAAAGTGCCAGCATTAAGCAAGGGACGGAATTACCTTACATTATGGTGAATGAAAAAAGTGGCACACAA
AGTGTGGAATTTCGCGAAGCCGTATTAGGGTTGGAAGTCACACCGCACATTTCCTTGGATAAGCAAATTCTGTTGGATTT
AATTGTGAGCCAAAACGCGCCGGGCAGCCGTGTGGCATACGGTTTAGGCGAGGTGGTTTCGATTGATAAACAAGAAATAA
ATACGCAAGTTTTTGCCAAGGACGGCGAAACCATCGTGCTTGGTGGCGTCTTTCACGACACCGTTACCAAAAGCTTAGAC
AAAGTGCCATTACTGGGAGACATTCCCGGCATTAAGCATTTATTTAGCAAAGAAAGTGATCGCCACCAAAAGCGGGAATT
GGTGATCTTCGTCACGCCACATATTTTGCGCCAGGGTGAGACATTGGAAAACTTGAAGAACAACCAGTCAACAGCGAAAA
AGAACAAGAAGCAAGAGAAATCCAAGACCGCACAAAACAAACCGAAAAAGGAAAGAAACCCGTAG

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (130-195)

• Bacterial type II and III secretion system protein (Secretin) (277-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	70.067	95.148	0.667
comE	Haemophilus influenzae 86-028NP	69.027	95.359	0.658
comE	Glaesserella parasuis strain SC1401	51.716	92.194	0.477
pilQ	Vibrio campbellii strain DS40M4	42.227	90.928	0.384
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	41.589	90.295	0.376
pilQ	Vibrio cholerae strain A1552	41.589	90.295	0.376