Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   J5Z97_RS00330 Genome accession   NZ_CP072112
Coordinates   53140..54051 (+) Length   303 a.a.
NCBI ID   WP_023611326.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M08500     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48140..59051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS00310 (J5Z97_00310) purE 48436..48927 (+) 492 WP_023611331.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  J5Z97_RS00315 (J5Z97_00315) purK 48914..49987 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  J5Z97_RS00320 (J5Z97_00320) - 50008..51348 (+) 1341 WP_208769272.1 hypothetical protein -
  J5Z97_RS00325 (J5Z97_00325) purB 51717..53009 (+) 1293 WP_023611333.1 adenylosuccinate lyase -
  J5Z97_RS00330 (J5Z97_00330) comR 53140..54051 (+) 912 WP_023611326.1 transcriptional regulator Rgg4/ComR Regulator
  J5Z97_RS00340 (J5Z97_00340) ruvB 54277..55275 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  J5Z97_RS00345 (J5Z97_00345) - 55413..55850 (+) 438 WP_063662030.1 low molecular weight protein-tyrosine-phosphatase -
  J5Z97_RS00350 (J5Z97_00350) - 55873..56274 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  J5Z97_RS00355 (J5Z97_00355) - 56271..58046 (+) 1776 WP_002987732.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35685.21 Da        Isoelectric Point: 4.5164

>NTDB_id=550450 J5Z97_RS00330 WP_023611326.1 53140..54051(+) (comR) [Streptococcus pyogenes strain M08500]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSGQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=550450 J5Z97_RS00330 WP_023611326.1 53140..54051(+) (comR) [Streptococcus pyogenes strain M08500]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGGACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

99.67

100

0.997
  comR Streptococcus pyogenes MGAS315

58.472

99.34

0.581
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.37

96.37

0.495
  comR Streptococcus mutans UA159

46.358

99.67

0.462