Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   J5D23_RS00215 Genome accession   NZ_CP071987
Coordinates   40056..41192 (+) Length   378 a.a.
NCBI ID   WP_209613999.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5136     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35056..46192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D23_RS00180 (J5D23_00180) panD 35480..35833 (+) 354 WP_000142286.1 aspartate 1-decarboxylase -
  J5D23_RS00185 (J5D23_00185) - 35836..36138 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  J5D23_RS00190 (J5D23_00190) - 36138..37142 (+) 1005 WP_209554406.1 PDZ domain-containing protein -
  J5D23_RS00195 (J5D23_00195) comB6 37150..38205 (+) 1056 WP_209554404.1 P-type conjugative transfer protein TrbL Machinery gene
  J5D23_RS00200 (J5D23_00200) comB7 38221..38334 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  J5D23_RS00205 (J5D23_00205) comB8 38331..39074 (+) 744 WP_209613997.1 virB8 family protein Machinery gene
  J5D23_RS00210 (J5D23_00210) comB9 39074..40063 (+) 990 WP_209613998.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  J5D23_RS00215 (J5D23_00215) comB10 40056..41192 (+) 1137 WP_209613999.1 DNA type IV secretion system protein ComB10 Machinery gene
  J5D23_RS00220 (J5D23_00220) - 41262..42680 (+) 1419 WP_209614000.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  J5D23_RS00225 (J5D23_00225) gmd 42690..43835 (+) 1146 WP_187863261.1 GDP-mannose 4,6-dehydratase -
  J5D23_RS00230 (J5D23_00230) - 43828..44760 (+) 933 WP_209614001.1 GDP-L-fucose synthase -
  J5D23_RS07835 - 44791..44966 (-) 176 Protein_40 anthranilate synthase component I -
  J5D23_RS00235 (J5D23_00235) - 45146..45430 (-) 285 WP_209614002.1 hypothetical protein -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 42155.60 Da        Isoelectric Point: 9.7760

>NTDB_id=549750 J5D23_RS00215 WP_209613999.1 40056..41192(+) (comB10) [Helicobacter pylori strain MT5136]
MNKWIKGAVVFVGGFITIITISLIYHQKPKAPSNNQPNLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNHAKEETFTSPPMDPKTNTTPPKKDFSPKQLDLLAARITPFKQSPKNYEENLIFPVDNPNGIDSFTNLKE
KDTATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFASMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEEVTNFFGDYLLLQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=549750 J5D23_RS00215 WP_209613999.1 40056..41192(+) (comB10) [Helicobacter pylori strain MT5136]
GTGAATAAGTGGATTAAAGGGGCGGTTGTTTTTGTAGGGGGTTTTATAACGATTATAACAATTTCTTTAATCTACCACCA
AAAGCCAAAAGCTCCCTCAAATAACCAACCCAATCTTTTGAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACGGAAAGCTCCAAAGACGCTACGATTAAAGCCTTACAAGAACAACTCAAAGCC
GCTTTAAAAGCCTTAAACTCCAAAGAAATGAACCATGCCAAAGAAGAAACTTTTACCAGCCCTCCCATGGATCCAAAAAC
AAACACAACCCCCCCTAAAAAAGATTTTTCTCCAAAGCAATTAGATTTACTAGCCGCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCTGTGGATAACCCTAATGGCATTGATAGTTTCACTAACCTTAAAGAA
AAAGACACCGCCACTAATGAAAACAAGCTTTTACGCACCATTACAGCTGACAAAATGATACCCGCTTTTTTGATCACGCC
CATTTCTAGCCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAAAGCGATATTTTTGCGAGCATGGGAAAGGCTGTTTTAA
TCCCCAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGT
CGAATCATCACTCCCCATGGCATTAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGCTTAGT
GGGGGAATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCTTATTGATTG
GGATCACTTCGGCTTTAAACAATAGAGGCAATAAAGAAGAGGTGACTAATTTCTTTGGGGATTATCTTTTATTGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTCGTCAATCAAATTTTAAGAGACAAAAGCAAGATCGCCCCCATTGTGGT
GATTAGAGAGGGAAGCAGGGTTTTCATTTCGCCCAATACTGATATATTCTTCCCTATACCCAGAGAGAATGAAGTCATCG
CAGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(173-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

93.915

100

0.939