Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   JN057_RS08730 Genome accession   NZ_CP071871
Coordinates   1697973..1698632 (+) Length   219 a.a.
NCBI ID   WP_000565003.1    Uniprot ID   A0A0E9GWM6
Organism   Streptococcus pneumoniae strain BVJ1JL     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1692973..1703632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN057_RS08705 (JN057_01782) - 1693278..1693595 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  JN057_RS08710 (JN057_01783) - 1693610..1694506 (-) 897 WP_000825669.1 PEP phosphonomutase -
  JN057_RS08715 (JN057_01784) - 1694509..1695771 (-) 1263 WP_000413339.1 PTS sugar transporter subunit IIC -
  JN057_RS08720 (JN057_01785) - 1696051..1697229 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  JN057_RS08725 (JN057_01786) - 1697457..1697903 (-) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  JN057_RS08730 (JN057_01787) cclA/cilC 1697973..1698632 (+) 660 WP_000565003.1 prepilin peptidase Machinery gene
  JN057_RS08735 (JN057_01788) - 1698684..1699835 (-) 1152 WP_000481750.1 helix-turn-helix domain-containing protein -
  JN057_RS08740 (JN057_01789) - 1699850..1700581 (-) 732 Protein_1741 hypothetical protein -
  JN057_RS08750 - 1700801..1700911 (+) 111 Protein_1742 prepilin peptidase -
  JN057_RS08755 (JN057_01791) trpA 1700883..1701659 (-) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  JN057_RS08760 (JN057_01792) trpB 1701652..1702875 (-) 1224 WP_000331296.1 tryptophan synthase subunit beta -
  JN057_RS08765 (JN057_01793) - 1702853..1703452 (-) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24841.94 Da        Isoelectric Point: 7.6166

>NTDB_id=548631 JN057_RS08730 WP_000565003.1 1697973..1698632(+) (cclA/cilC) [Streptococcus pneumoniae strain BVJ1JL]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=548631 JN057_RS08730 WP_000565003.1 1697973..1698632(+) (cclA/cilC) [Streptococcus pneumoniae strain BVJ1JL]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E9GWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868