Detailed information NTG0548412

Bioinformatically predicted

Overview

• Name: tfoX
• Type: Regulator
• Locus tag: J4N37_RS09960
• Genome accession: NZ_CP071855
• Coordinates: 2054767..2055348 (-)
• Length: 193 a.a.
• NCBI ID: WP_010448582.1
• Uniprot ID: A0A2K7SUV4
• Organism: Vibrio sp. SCSIO 43153
• Function: master regulator of natural competence (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2047415..2058276	2054767..2055348	within	0

Gene organization within MGE regions

Location: 2047415..2058276

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4N37_RS09930 (J4N37_09795)	-	2047415..2048584 (-)	1170	WP_038887585.1	extracellular solute-binding protein	-
J4N37_RS09935 (J4N37_09800)	serC	2048749..2049843 (-)	1095	WP_162531061.1	3-phosphoserine/phosphohydroxythreonine transaminase	-
J4N37_RS09940 (J4N37_09805)	-	2049975..2051237 (-)	1263	WP_010448589.1	DUF945 family protein	-
J4N37_RS09945 (J4N37_09810)	-	2051424..2053367 (+)	1944	WP_252040790.1	ATP-binding protein	-
J4N37_RS09950 (J4N37_09815)	-	2053360..2053857 (+)	498	WP_010448586.1	response regulator	-
J4N37_RS09955 (J4N37_09820)	-	2054065..2054613 (+)	549	WP_038887578.1	hypothetical protein	-
J4N37_RS09960 (J4N37_09825)	tfoX	2054767..2055348 (-)	582	WP_010448582.1	TfoX/Sxy family DNA transformation protein	Regulator
J4N37_RS09965 (J4N37_09830)	-	2055718..2056638 (+)	921	WP_045388466.1	HDOD domain-containing protein	-
J4N37_RS09970 (J4N37_09835)	-	2056703..2057608 (+)	906	WP_038884532.1	lysine exporter LysO family protein	-
J4N37_RS09975 (J4N37_09840)	-	2057764..2058276 (+)	513	WP_038884533.1	hypothetical protein	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 22114.70 Da
• Isoelectric Point: 8.8608

>NTDB_id=548412 J4N37_RS09960 WP_010448582.1 2054767..2055348(-) (tfoX) [Vibrio sp. SCSIO 43153]
MTDQAFFTYIKKFKSFQKRSMFGGIGLFSDDAMFALVSNDCCYLRGGKELDQIFVDLECEKYKHVKKQTTATVNYYDVTE
LFEARAPELDKLVVKSIACSVREREFQKSSASKRLRDLPNMQLTLERMVKKAGIDDVETFLALGPVEVFNKVRAAYGSDV
DLKLLWKFAGAVDGVHWKLIQEPRKKQLLSLCQ

Nucleotide

• Length: 582 bp

>NTDB_id=548412 J4N37_RS09960 WP_010448582.1 2054767..2055348(-) (tfoX) [Vibrio sp. SCSIO 43153]
ATGACAGACCAAGCTTTTTTTACTTATATAAAAAAATTTAAATCTTTCCAAAAGCGCTCTATGTTTGGTGGTATAGGGCT
TTTTAGTGACGATGCTATGTTTGCATTAGTAAGCAATGACTGCTGCTACCTTCGCGGCGGAAAAGAACTAGACCAAATAT
TTGTCGACTTGGAGTGTGAGAAATACAAACACGTTAAAAAGCAAACAACGGCCACAGTAAATTACTACGACGTTACTGAG
CTGTTTGAGGCTCGCGCACCAGAGTTAGATAAGCTCGTTGTTAAGTCAATAGCATGTTCTGTACGAGAGAGAGAGTTCCA
AAAATCTTCTGCTAGTAAAAGACTACGTGATTTGCCGAATATGCAGCTTACGCTTGAGCGTATGGTTAAGAAGGCAGGCA
TTGACGATGTTGAAACATTCTTAGCGTTGGGACCTGTAGAAGTTTTCAATAAAGTTCGAGCGGCTTACGGCAGTGATGTT
GATCTAAAGTTGCTTTGGAAGTTTGCCGGAGCGGTAGACGGCGTTCATTGGAAGCTTATCCAAGAGCCAAGAAAGAAACA
GCTATTATCTCTTTGTCAATAG

Domains

Predicted by InterproScan.

• TfoX N-terminal domain (TfoX_N) (10-99)

• TfoX C-terminal domain (TfoX_C) (112-189)

3D structure

• AlphaFold DB: A0A2K7SUV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
tfoX	Vibrio parahaemolyticus RIMD 2210633	81.865	100	0.819
tfoX	Vibrio campbellii strain DS40M4	79.793	100	0.798
tfoX	Vibrio cholerae O1 biovar El Tor str. N16961	70.984	100	0.71
tfoX	Vibrio cholerae O1 biovar El Tor strain DRC-193A	70.984	100	0.71
tfoX	Vibrio cholerae O1 biovar El Tor strain P27459	70.984	100	0.71
tfoX	Vibrio cholerae O1 biovar El Tor strain E7946	70.984	100	0.71
tfoX	Vibrio cholerae strain A1552	70.984	100	0.71
tfoX	Aliivibrio fischeri ES114	60.428	96.891	0.585