Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LSI69_RS00395 Genome accession   NZ_CP089032
Coordinates   81528..82118 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli O157:H7 strain 6535WT     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 76528..87118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSI69_RS00375 (LSI69_00375) ilvN 77819..78109 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  LSI69_RS00380 (LSI69_00380) - 78372..79025 (+) 654 WP_000168040.1 hypothetical protein -
  LSI69_RS00385 (LSI69_00385) - 79173..79655 (+) 483 WP_000229982.1 hypothetical protein -
  LSI69_RS00390 (LSI69_00390) - 80263..81366 (+) 1104 WP_001089794.1 hypothetical protein -
  LSI69_RS00395 (LSI69_00395) letA 81528..82118 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  LSI69_RS00400 (LSI69_00400) uhpB 82118..83620 (+) 1503 WP_001303725.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  LSI69_RS00405 (LSI69_00405) uhpC 83630..84949 (+) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  LSI69_RS00410 (LSI69_00410) uhpT 85087..86478 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=547760 LSI69_RS00395 WP_000633668.1 81528..82118(+) (letA) [Escherichia coli O157:H7 strain 6535WT]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=547760 LSI69_RS00395 WP_000633668.1 81528..82118(+) (letA) [Escherichia coli O157:H7 strain 6535WT]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGTGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCACTAACCAAACGTGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378