Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   J1N58_RS04820 Genome accession   NZ_CP071697
Coordinates   995361..996740 (+) Length   459 a.a.
NCBI ID   WP_207560579.1    Uniprot ID   A0A9X4MMU1
Organism   Streptococcus suis strain 1112S     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 990361..1001740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS04790 (J1N58_04790) pstA 990851..991738 (+) 888 WP_044757644.1 phosphate ABC transporter permease PstA -
  J1N58_RS04795 (J1N58_04795) pstB 991763..992566 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  J1N58_RS04800 (J1N58_04800) pstB 992578..993336 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  J1N58_RS04805 (J1N58_04805) phoU 993365..994021 (+) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  J1N58_RS04810 (J1N58_04810) - 994171..994551 (+) 381 WP_105147512.1 hypothetical protein -
  J1N58_RS04815 (J1N58_04815) ciaR 994697..995368 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  J1N58_RS04820 (J1N58_04820) ciaH 995361..996740 (+) 1380 WP_207560579.1 HAMP domain-containing sensor histidine kinase Regulator
  J1N58_RS04825 (J1N58_04825) - 996841..998070 (+) 1230 WP_024376493.1 transglutaminase domain-containing protein -
  J1N58_RS04830 (J1N58_04830) rpsT 998334..998582 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  J1N58_RS04835 (J1N58_04835) coaA 998641..999561 (-) 921 WP_002935283.1 type I pantothenate kinase -
  J1N58_RS04840 (J1N58_04840) - 999670..1000260 (+) 591 WP_207560580.1 class I SAM-dependent methyltransferase -
  J1N58_RS04845 (J1N58_04845) - 1000257..1001534 (+) 1278 WP_024413752.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51960.57 Da        Isoelectric Point: 5.6032

>NTDB_id=547046 J1N58_RS04820 WP_207560579.1 995361..996740(+) (ciaH) [Streptococcus suis strain 1112S]
MPKRIRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPEDQKNTRDVDQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=547046 J1N58_RS04820 WP_207560579.1 995361..996740(+) (ciaH) [Streptococcus suis strain 1112S]
ATGCCTAAGCGAATCAGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGTTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTGAAGATCAAAAAAATACTAGAGATGT
AGATCAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAGATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CTTGGCTCATTTCTATCTTAGCCAGTATTTACCTATCGAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTTGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCTTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATCAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae D39

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae R6

49.782

99.782

0.497
  ciaH Streptococcus pneumoniae TIGR4

49.782

99.782

0.497
  ciaH Streptococcus mutans UA159

49.451

99.129

0.49