Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   J1N58_RS02400 Genome accession   NZ_CP071697
Coordinates   490669..491961 (+) Length   430 a.a.
NCBI ID   WP_029997070.1    Uniprot ID   A0A9X4RTK5
Organism   Streptococcus suis strain 1112S     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 485669..496961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS02375 (J1N58_02375) - 486474..487115 (+) 642 WP_002937025.1 response regulator transcription factor -
  J1N58_RS02380 (J1N58_02380) - 487165..488565 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  J1N58_RS02385 (J1N58_02385) - 488567..488938 (+) 372 WP_029178257.1 S1 RNA-binding domain-containing protein -
  J1N58_RS02390 (J1N58_02390) cysK 488964..489890 (-) 927 WP_105096272.1 cysteine synthase A -
  J1N58_RS02395 (J1N58_02395) - 489980..490612 (-) 633 WP_161940868.1 YigZ family protein -
  J1N58_RS02400 (J1N58_02400) comFA/cflA 490669..491961 (+) 1293 WP_029997070.1 DEAD/DEAH box helicase Machinery gene
  J1N58_RS02405 (J1N58_02405) comFC/cflB 491954..492619 (+) 666 WP_024419560.1 ComF family protein Machinery gene
  J1N58_RS02410 (J1N58_02410) raiA 492697..493239 (+) 543 WP_014637536.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48989.58 Da        Isoelectric Point: 9.0315

>NTDB_id=547039 J1N58_RS02400 WP_029997070.1 490669..491961(+) (comFA/cflA) [Streptococcus suis strain 1112S]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEDGVQVFLTATSTDEL
DKKVRMGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=547039 J1N58_RS02400 WP_029997070.1 490669..491961(+) (comFA/cflA) [Streptococcus suis strain 1112S]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTAACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAGCTTTATCATTTTCCTCAGAAAGATTTT
CCAATTACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTAGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGATAATGCGGTCAAGGAAGACGGAGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAATGGGTAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCTAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTCGTTCAGATTGCAGGCCGGGTCGGCAGGAGTATGGAGCGTCCGACTGGT
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363