Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   JZY07_RS04405 Genome accession   NZ_CP071305
Coordinates   872940..874319 (+) Length   459 a.a.
NCBI ID   WP_105155592.1    Uniprot ID   -
Organism   Streptococcus suis strain SC183     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 867940..879319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZY07_RS04375 (JZY07_04375) pstA 868399..869286 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  JZY07_RS04380 (JZY07_04380) pstB 869311..870114 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  JZY07_RS04385 (JZY07_04385) pstB 870126..870884 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  JZY07_RS04390 (JZY07_04390) phoU 870913..871569 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  JZY07_RS04395 (JZY07_04395) - 871735..872082 (+) 348 WP_014635995.1 hypothetical protein -
  JZY07_RS04400 (JZY07_04400) ciaR 872276..872947 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  JZY07_RS04405 (JZY07_04405) ciaH 872940..874319 (+) 1380 WP_105155592.1 HAMP domain-containing sensor histidine kinase Regulator
  JZY07_RS11580 - 874420..875139 (+) 720 WP_242513108.1 transglutaminase domain-containing protein -
  JZY07_RS11585 - 875102..875650 (+) 549 WP_242513109.1 hypothetical protein -
  JZY07_RS04415 (JZY07_04415) rpsT 875866..876114 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  JZY07_RS04420 (JZY07_04420) coaA 876173..877093 (-) 921 WP_002935283.1 type I pantothenate kinase -
  JZY07_RS04425 (JZY07_04425) - 877202..877792 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  JZY07_RS04430 (JZY07_04430) - 877789..879066 (+) 1278 WP_024389005.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51839.50 Da        Isoelectric Point: 6.5295

>NTDB_id=544864 JZY07_RS04405 WP_105155592.1 872940..874319(+) (ciaH) [Streptococcus suis strain SC183]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKILTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=544864 JZY07_RS04405 WP_105155592.1 872940..874319(+) (ciaH) [Streptococcus suis strain SC183]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCAACAGTTGCTATTGTTATGGTTTCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCCCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAATACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae D39

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae R6

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae TIGR4

49.563

99.782

0.495
  ciaH Streptococcus mutans UA159

50.112

97.386

0.488