Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LO009_RS15355 Genome accession   NZ_CP087298
Coordinates   3222543..3223217 (-) Length   224 a.a.
NCBI ID   WP_000161506.1    Uniprot ID   G1CBK2
Organism   Acinetobacter baumannii strain OC070     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3217543..3228217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LO009_RS15335 - 3217957..3218841 (+) 885 WP_138149472.1 LysR family transcriptional regulator -
  LO009_RS15340 - 3219144..3220331 (+) 1188 WP_001181774.1 ammonium transporter -
  LO009_RS15345 - 3220484..3221182 (+) 699 WP_000184469.1 phosphatase PAP2 family protein -
  LO009_RS15350 - 3221183..3222517 (-) 1335 WP_000559381.1 two-component system sensor histidine kinase PmrB -
  LO009_RS15355 ciaR 3222543..3223217 (-) 675 WP_000161506.1 DNA-binding response regulator PmrA Regulator
  LO009_RS15360 - 3223232..3224881 (-) 1650 WP_138149474.1 phosphoethanolamine transferase -
  LO009_RS15365 - 3225060..3226364 (-) 1305 WP_029424805.1 DcaP family trimeric outer membrane transporter -
  LO009_RS15370 - 3226909..3228156 (-) 1248 WP_138149476.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25562.50 Da        Isoelectric Point: 5.3246

>NTDB_id=544655 LO009_RS15355 WP_000161506.1 3222543..3223217(-) (ciaR) [Acinetobacter baumannii strain OC070]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRTGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=544655 LO009_RS15355 WP_000161506.1 3222543..3223217(-) (ciaR) [Acinetobacter baumannii strain OC070]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTAAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAATCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAGTTTGATGA
GTTGCTTGCTCGTATTCATGCATTACTACGCCGTACTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATTCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGACAGTCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G1CBK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.053

100

0.384
  ciaR Streptococcus pneumoniae D39

38.053

100

0.384
  ciaR Streptococcus pneumoniae R6

38.053

100

0.384
  ciaR Streptococcus pneumoniae TIGR4

38.053

100

0.384
  ciaR Streptococcus mutans UA159

37.004

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.526

100

0.362