Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   JYQ80_RS00265 Genome accession   NZ_CP070994
Coordinates   47092..48003 (+) Length   303 a.a.
NCBI ID   WP_002986681.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M11318     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 42092..53003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JYQ80_RS00245 (JYQ80_00245) purE 42429..42920 (+) 492 WP_015055884.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  JYQ80_RS00250 (JYQ80_00250) purK 42907..43980 (+) 1074 WP_015055885.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  JYQ80_RS00255 (JYQ80_00255) - 44007..45650 (+) 1644 WP_010921779.1 AIPR family protein -
  JYQ80_RS00260 (JYQ80_00260) purB 45668..46960 (+) 1293 WP_010921780.1 adenylosuccinate lyase -
  JYQ80_RS00265 (JYQ80_00265) comR 47092..48003 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  JYQ80_RS09330 (JYQ80_00270) comS 48087..48182 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  JYQ80_RS00275 (JYQ80_00275) ruvB 48229..49227 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  JYQ80_RS00280 (JYQ80_00280) - 49365..49802 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  JYQ80_RS00285 (JYQ80_00285) - 49825..50226 (+) 402 WP_010921781.1 MORN repeat-containing protein -
  JYQ80_RS00290 (JYQ80_00290) - 50223..51998 (+) 1776 WP_010921782.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35757.27 Da        Isoelectric Point: 4.4858

>NTDB_id=541998 JYQ80_RS00265 WP_002986681.1 47092..48003(+) (comR) [Streptococcus pyogenes strain M11318]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=541998 JYQ80_RS00265 WP_002986681.1 47092..48003(+) (comR) [Streptococcus pyogenes strain M11318]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGAACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

100

100

1
  comR Streptococcus pyogenes MGAS315

58.472

99.34

0.581
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.37

96.37

0.495
  comR Streptococcus mutans UA159

46.358

99.67

0.462