Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LL046_RS02025 Genome accession   NZ_CP086088
Coordinates   387920..389362 (-) Length   480 a.a.
NCBI ID   WP_240819039.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain EIP13A     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 382920..394362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL046_RS02000 (LL046_01985) nox 382954..384294 (+) 1341 WP_023188995.1 H2O-forming NADH oxidase -
  LL046_RS02005 (LL046_01990) - 384381..384772 (+) 392 Protein_383 single-stranded DNA-binding protein -
  LL046_RS02010 (LL046_01995) groES 384892..385176 (+) 285 WP_003131589.1 co-chaperone GroES -
  LL046_RS02015 (LL046_02000) groL 385264..386892 (+) 1629 WP_003131585.1 chaperonin GroEL -
  LL046_RS02020 (LL046_02005) vicX 386939..387751 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  LL046_RS02025 (LL046_02010) vicK 387920..389362 (-) 1443 WP_240819039.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LL046_RS02030 (LL046_02015) yycF 389355..390056 (-) 702 WP_003131580.1 response regulator YycF -
  LL046_RS02035 (LL046_02020) tmk 390234..390869 (+) 636 WP_012897230.1 dTMP kinase -
  LL046_RS02040 (LL046_02025) - 391002..391862 (+) 861 WP_058203378.1 DNA polymerase III subunit delta' -
  LL046_RS02045 (LL046_02030) yaaT 391914..392696 (+) 783 WP_211752553.1 stage 0 sporulation family protein Regulator
  LL046_RS02050 (LL046_02035) yabA 392689..393015 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  LL046_RS02055 (LL046_02040) rsmI 393015..393890 (+) 876 WP_211752552.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LL046_RS02060 (LL046_02045) - 393967..394158 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54596.07 Da        Isoelectric Point: 4.5536

>NTDB_id=540255 LL046_RS02025 WP_240819039.1 387920..389362(-) (vicK) [Lactococcus lactis subsp. lactis strain EIP13A]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRCGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=540255 LL046_RS02025 WP_240819039.1 387920..389362(-) (vicK) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTTGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCGTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACACTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

PAS domain (PAS_9)

(124-220)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.523

92.5

0.44