Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GGS_RS02960 Genome accession   NC_018712
Coordinates   576751..577458 (+) Length   235 a.a.
NCBI ID   WP_003055001.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis RE378     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 571751..582458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GGS_RS02930 (GGS_0557) - 571780..573204 (+) 1425 WP_015016792.1 glycoside hydrolase family 1 protein -
  GGS_RS02935 (GGS_0558) - 573303..574118 (-) 816 WP_042357866.1 TIGR03943 family protein -
  GGS_RS02940 (GGS_0559) - 574118..575020 (-) 903 WP_015016794.1 permease -
  GGS_RS02950 (GGS_0560) - 575402..576013 (-) 612 WP_015016795.1 NUDIX hydrolase N-terminal domain-containing protein -
  GGS_RS02955 (GGS_0561) - 576182..576664 (+) 483 WP_015016796.1 cupin domain-containing protein -
  GGS_RS02960 (GGS_0562) vicR 576751..577458 (+) 708 WP_003055001.1 response regulator transcription factor Regulator
  GGS_RS02965 (GGS_0563) - 577459..578787 (+) 1329 WP_015016797.1 two-component system histidine kinase PnpS -
  GGS_RS02970 (GGS_0564) - 578954..579829 (+) 876 WP_003055008.1 substrate-binding domain-containing protein -
  GGS_RS02975 (GGS_0565) pstC 579947..580810 (+) 864 WP_012766699.1 phosphate ABC transporter permease subunit PstC -
  GGS_RS02980 (GGS_0566) pstA 580803..581618 (+) 816 WP_003060853.1 phosphate ABC transporter permease PstA -
  GGS_RS02985 (GGS_0567) pstB 581620..582372 (+) 753 WP_015016798.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27491.70 Da        Isoelectric Point: 5.4461

>NTDB_id=53957 GGS_RS02960 WP_003055001.1 576751..577458(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MTKQILLVDDEEHILRLLDYHLGKEGFSTQLVTDGRKALTLAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAILRRTSKEQQEDDTDDFRDDYRVFGALTVYPDRHEVYKADHLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDNPKDPQFIQTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=53957 GGS_RS02960 WP_003055001.1 576751..577458(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
ATGACAAAACAAATCTTATTAGTGGATGATGAAGAACACATTTTGAGGCTACTGGATTATCATCTCGGTAAAGAAGGGTT
TTCCACACAATTGGTAACAGATGGCCGAAAAGCATTGACATTGGCAGAAACAGAGCCTTTTGACTTTATCCTACTGGATA
TTATGTTGCCTCAGTTAGACGGCATAGAAGTGTGTAAGCGACTGAGAGCTAAAGGAATAAAAACTCCGATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGAGCTGATGACTACCTGACTAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTATTTTACGTCGAACCAGTAAAGAGCAGCAAGAAGATGACACAGATGATTTCA
GGGATGATTATCGGGTATTTGGGGCCCTGACCGTCTATCCAGACCGGCATGAGGTTTATAAGGCAGATCATTTATTGAGC
CTTACCCCAAAGGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACATTAACTAGGGAACGTTTACTTGA
ACGGATTTGGGGATATGATTTTGGACAAGAAACCCGTTTAGTGGATGTTCATATTGGCAAATTGAGAGATAAGATAGAGG
ATAATCCTAAAGACCCTCAATTTATTCAAACGATTAGAGGCTATGGGTATAAGTTTAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

49.145

99.574

0.489
  micA Streptococcus pneumoniae Cp1015

47.619

98.298

0.468
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.772

100

0.421
  covR Streptococcus salivarius strain HSISS4

40.506

100

0.409

Multiple sequence alignment