Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | I6K34_RS20740 | Genome accession | NZ_CP069990 |
| Coordinates | 4267825..4268949 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228509.1 | Uniprot ID | - |
| Organism | Escherichia coli strain FDAARGOS_1304 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 4245978..4268949 | 4267825..4268949 | within | 0 |
Gene organization within MGE regions
Location: 4245978..4268949
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K34_RS20550 (I6K34_20550) | gspA | 4245978..4247447 (+) | 1470 | WP_000107586.1 | type II secretion system protein GspA | - |
| I6K34_RS20555 (I6K34_20555) | gspB | 4247449..4247868 (+) | 420 | WP_000461443.1 | putative general secretion pathway protein GspB | - |
| I6K34_RS20560 (I6K34_20560) | rpsJ | 4248106..4248417 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| I6K34_RS20565 (I6K34_20565) | rplC | 4248450..4249079 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| I6K34_RS20570 (I6K34_20570) | rplD | 4249090..4249695 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| I6K34_RS20575 (I6K34_20575) | rplW | 4249692..4249994 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| I6K34_RS20580 (I6K34_20580) | rplB | 4250012..4250833 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| I6K34_RS20585 (I6K34_20585) | rpsS | 4250850..4251128 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| I6K34_RS20590 (I6K34_20590) | rplV | 4251143..4251475 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| I6K34_RS20595 (I6K34_20595) | rpsC | 4251493..4252194 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| I6K34_RS20600 (I6K34_20600) | rplP | 4252207..4252617 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| I6K34_RS20605 (I6K34_20605) | rpmC | 4252617..4252808 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| I6K34_RS20610 (I6K34_20610) | rpsQ | 4252808..4253062 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| I6K34_RS20615 (I6K34_20615) | rplN | 4253227..4253598 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| I6K34_RS20620 (I6K34_20620) | rplX | 4253609..4253923 (+) | 315 | WP_000729186.1 | 50S ribosomal protein L24 | - |
| I6K34_RS20625 (I6K34_20625) | rplE | 4253938..4254477 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| I6K34_RS20630 (I6K34_20630) | rpsN | 4254492..4254797 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| I6K34_RS20635 (I6K34_20635) | rpsH | 4254831..4255223 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| I6K34_RS20640 (I6K34_20640) | rplF | 4255236..4255769 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| I6K34_RS20645 (I6K34_20645) | rplR | 4255779..4256132 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| I6K34_RS20650 (I6K34_20650) | rpsE | 4256147..4256650 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| I6K34_RS20655 (I6K34_20655) | rpmD | 4256654..4256833 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| I6K34_RS20660 (I6K34_20660) | rplO | 4256837..4257271 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| I6K34_RS20665 (I6K34_20665) | secY | 4257279..4258610 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| I6K34_RS20670 (I6K34_20670) | rpmJ | 4258642..4258758 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| I6K34_RS20675 (I6K34_20675) | rpsM | 4258905..4259261 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| I6K34_RS20680 (I6K34_20680) | rpsK | 4259278..4259667 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| I6K34_RS20685 (I6K34_20685) | rpsD | 4259701..4260321 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| I6K34_RS20690 (I6K34_20690) | rpoA | 4260347..4261336 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| I6K34_RS20695 (I6K34_20695) | rplQ | 4261377..4261760 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| I6K34_RS20700 (I6K34_20700) | yhdN | 4261867..4262235 (+) | 369 | WP_000266504.1 | DUF1992 domain-containing protein | - |
| I6K34_RS20705 (I6K34_20705) | zntR | 4262246..4262671 (+) | 426 | WP_000285610.1 | Zn(2+)-responsive transcriptional regulator | - |
| I6K34_RS20710 (I6K34_20710) | arfA | 4262727..4262945 (+) | 219 | WP_000092695.1 | alternative ribosome-rescue factor ArfA | - |
| I6K34_RS20715 (I6K34_20715) | mscL | 4262942..4263355 (-) | 414 | WP_000022450.1 | large-conductance mechanosensitive channel protein MscL | - |
| I6K34_RS20720 (I6K34_20720) | trkA | 4263485..4264861 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| I6K34_RS20725 (I6K34_20725) | rsmB | 4264883..4266172 (-) | 1290 | WP_000744766.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| I6K34_RS20730 (I6K34_20730) | fmt | 4266224..4267171 (-) | 948 | WP_000004421.1 | methionyl-tRNA formyltransferase | - |
| I6K34_RS20735 (I6K34_20735) | def | 4267186..4267695 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| I6K34_RS20740 (I6K34_20740) | dprA | 4267825..4268949 (+) | 1125 | WP_000228509.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 40991.96 Da Isoelectric Point: 6.1815
>NTDB_id=537751 I6K34_RS20740 WP_000228509.1 4267825..4268949(+) (dprA) [Escherichia coli strain FDAARGOS_1304]
MVDTEIWLRLISISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWRRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLISISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWRRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=537751 I6K34_RS20740 WP_000228509.1 4267825..4268949(+) (dprA) [Escherichia coli strain FDAARGOS_1304]
ATGGTTGATACAGAAATTTGGCTGCGTTTAATTAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGAGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTTGATACAGAAATTTGGCTGCGTTTAATTAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGAGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Vibrio cholerae strain A1552 |
49.032 |
82.888 |
0.406 |
| dprA | Glaesserella parasuis strain SC1401 |
44.807 |
90.107 |
0.404 |
| dprA | Haemophilus influenzae Rd KW20 |
43.917 |
90.107 |
0.396 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.242 |
88.235 |
0.39 |