Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   STRSA0001_RS01070 Genome accession   NZ_ACLO01000018
Coordinates   37929..38666 (+) Length   245 a.a.
NCBI ID   WP_002883766.1    Uniprot ID   -
Organism   Streptococcus salivarius SK126     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 32929..43666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STRSA0001_RS01050 (STRSA0001_1744) - 33525..34046 (-) 522 WP_002883807.1 GNAT family N-acetyltransferase -
  STRSA0001_RS01055 (STRSA0001_1745) tsaE 34039..34482 (-) 444 WP_002883769.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  STRSA0001_RS01060 (STRSA0001_1746) - 34758..36179 (-) 1422 WP_002883789.1 NCS2 family permease -
  STRSA0001_RS01065 (STRSA0001_1747) - 36388..37200 (+) 813 WP_002883805.1 HAD family hydrolase -
  STRSA0001_RS01070 (STRSA0001_1748) comE/blpR 37929..38666 (+) 738 WP_002883766.1 LytR/AlgR family response regulator transcription factor Regulator
  STRSA0001_RS10400 comD/comD3 39320..39871 (+) 552 WP_157747901.1 GHKL domain-containing protein Regulator
  STRSA0001_RS01080 (STRSA0001_1750) - 40017..41084 (-) 1068 WP_002883808.1 HlyD family efflux transporter periplasmic adaptor subunit -
  STRSA0001_RS01085 (STRSA0001_1751) comA/nlmT 41102..43258 (-) 2157 WP_002883725.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28536.61 Da        Isoelectric Point: 7.0641

>NTDB_id=53730 STRSA0001_RS01070 WP_002883766.1 37929..38666(+) (comE/blpR) [Streptococcus salivarius SK126]
MDIYILEDNIIQQGRLEQALDKALRSYGETLDCVQTFEQSNQLLEYIKPANHQQLFFLDIEIKGKEKEGLHLGQTIRNKL
PDAHIVFVTSHSEFMPLTFSYQLFALDYIDKNLDEDSFQSKVAIALSYVAKQSIKKEEKFSFHSGTDHIDLSYDRLLYIE
TSAKRHYVILHGSHSIFEFRANISDLANANPKLFRCHRSYLINPDKLVRLNKTKREIEMSDGTNCLVSRRHIKAVLAFMY
EDKKI

Nucleotide


Download         Length: 738 bp        

>NTDB_id=53730 STRSA0001_RS01070 WP_002883766.1 37929..38666(+) (comE/blpR) [Streptococcus salivarius SK126]
ATGGATATCTACATTTTAGAGGACAACATAATACAGCAAGGTAGATTGGAACAGGCTCTGGATAAGGCTCTCAGATCCTA
TGGTGAGACACTAGACTGTGTCCAGACCTTTGAACAATCCAACCAACTTCTGGAATATATAAAGCCAGCCAACCATCAAC
AACTCTTTTTCTTGGATATTGAGATTAAAGGGAAAGAAAAAGAAGGACTCCATTTGGGACAAACCATCCGAAACAAACTA
CCAGATGCTCATATTGTCTTTGTAACCTCCCACTCAGAGTTTATGCCCTTAACTTTTAGTTACCAACTCTTTGCCCTAGA
CTATATCGACAAAAATCTAGATGAAGATTCTTTTCAATCAAAGGTCGCGATAGCCCTATCCTATGTCGCTAAGCAAAGTA
TAAAAAAAGAGGAAAAGTTCTCTTTTCATTCTGGAACCGACCATATCGATCTCTCCTATGACCGTTTGCTTTATATTGAA
ACATCTGCTAAAAGGCACTATGTTATCTTACACGGTTCCCATAGCATTTTTGAGTTTCGAGCCAATATCTCAGACTTAGC
TAATGCCAATCCTAAGCTCTTCCGCTGTCATCGCTCCTACCTAATCAACCCTGACAAATTGGTACGTCTCAATAAGACCA
AACGCGAAATCGAAATGTCAGACGGCACTAACTGTCTGGTATCTCGTAGACATATCAAGGCAGTCTTAGCCTTTATGTAT
GAGGATAAGAAGATATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(151-235)

Response regulator receiver domain (Response_reg)

(4-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

37.247

100

0.376
  comE/comE2 Streptococcus equinus JB1

36.777

98.776

0.363
  comE/comE1 Streptococcus equinus JB1

36.929

98.367

0.363

Multiple sequence alignment