Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1099_RS05400 Genome accession   NZ_CP069796
Coordinates   1137817..1139019 (-) Length   400 a.a.
NCBI ID   WP_005608031.1    Uniprot ID   A0A828PSQ1
Organism   Actinobacillus pleuropneumoniae serovar 6 str. Femo     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1132817..1144019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1099_RS05375 (D1099_05340) lptE 1134617..1135111 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1099_RS05380 (D1099_05345) holA 1135220..1136245 (+) 1026 WP_005608028.1 DNA polymerase III subunit delta -
  D1099_RS05385 (D1099_05350) yacG 1136322..1136510 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1099_RS05390 (D1099_05355) coaE 1136492..1137130 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1099_RS05395 (D1099_05360) - 1137152..1137790 (-) 639 WP_005604550.1 prepilin peptidase -
  D1099_RS05400 (D1099_05365) pilC 1137817..1139019 (-) 1203 WP_005608031.1 type II secretion system F family protein Machinery gene
  D1099_RS05405 (D1099_05370) pilB 1139003..1140397 (-) 1395 WP_005601209.1 GspE/PulE family protein Machinery gene
  D1099_RS05410 (D1099_05375) pilA 1140415..1140861 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1099_RS05415 (D1099_05380) radA 1141043..1142422 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1099_RS05420 (D1099_05385) - 1142466..1142699 (-) 234 WP_005597399.1 YgjV family protein -
  D1099_RS05425 (D1099_05390) folA 1142826..1143314 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45618.11 Da        Isoelectric Point: 10.3239

>NTDB_id=536686 D1099_RS05400 WP_005608031.1 1137817..1139019(-) (pilC) [Actinobacillus pleuropneumoniae serovar 6 str. Femo]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSHFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLTAQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=536686 D1099_RS05400 WP_005608031.1 1137817..1139019(-) (pilC) [Actinobacillus pleuropneumoniae serovar 6 str. Femo]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCACTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTACTGCACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A828PSQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.25

0.495
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39