Detailed information NTG0535509

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6J38_RS01975
• Genome accession: NZ_CP069558
• Coordinates: 403119..405347 (+)
• Length: 742 a.a.
• NCBI ID: WP_020997762.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain FDAARGOS_1208
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 398119..410347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J38_RS01950 (I6J38_01950)	rpmG	398980..399129 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
I6J38_RS01955 (I6J38_01955)	secG	399169..399402 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6J38_RS01960 (I6J38_01960)	rnr	399495..401631 (+)	2137	Protein_396	ribonuclease R	-
I6J38_RS01965 (I6J38_01965)	smpB	401797..402264 (+)	468	WP_006267184.1	SsrA-binding protein SmpB	-
I6J38_RS01970 (I6J38_01970)	-	402432..403135 (+)	704	Protein_398	helix-hairpin-helix domain-containing protein	-
I6J38_RS01975 (I6J38_01975)	comEC/celB	403119..405347 (+)	2229	WP_020997762.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6J38_RS10040	-	405519..405914 (+)	396	WP_420918606.1	DUF805 domain-containing protein	-
I6J38_RS10045	-	406005..406145 (+)	141	WP_022525502.1	hypothetical protein	-
I6J38_RS01985 (I6J38_01985)	-	406590..407576 (+)	987	WP_020997763.1	Gfo/Idh/MocA family protein	-
I6J38_RS01990 (I6J38_01990)	-	407598..408251 (+)	654	WP_003034489.1	uracil-DNA glycosylase	-
I6J38_RS01995 (I6J38_01995)	-	408288..408758 (+)	471	WP_003031692.1	NUDIX hydrolase	-
I6J38_RS02000 (I6J38_02000)	-	408771..410048 (+)	1278	WP_020997764.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85327.29 Da
• Isoelectric Point: 9.9939

>NTDB_id=535509 I6J38_RS01975 WP_020997762.1 403119..405347(+) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1208]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCLIFLIVRLFVLYSPKKCFTTLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANGQTYQIYYKLKSKEEQLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQVY
LKTQGIYRNLKVDQILSSQDRVSFQPFEWLSSWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPLQNEITMVDVGQGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVLKVVKKFAVKKIFISRSSLNDADFLNKLKETKTFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=535509 I6J38_RS01975 WP_020997762.1 403119..405347(+) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1208]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTCTTATTTTTCTAATAGTCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCACAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGTAA
AGCAAATGGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGTCTAT
CTAAAAACACAAGGGATTTATCGAAATTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGTTGTCTAGCTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGACAGGGAGATAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTGATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTATTAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAAGACGTTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCCAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-577)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	54.826	100	0.551
comEC/celB	Streptococcus mitis SK321	54.752	100	0.551
comEC/celB	Streptococcus pneumoniae TIGR4	53.949	100	0.543
comEC/celB	Streptococcus pneumoniae Rx1	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae D39	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae R6	53.146	100	0.535
comEC	Lactococcus lactis subsp. cremoris KW2	46.433	100	0.465