Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | I6J97_RS01975 | Genome accession | NZ_CP069522 |
| Coordinates | 390934..392058 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228517.1 | Uniprot ID | E2QFE2 |
| Organism | Escherichia coli strain FDAARGOS_1267 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 369087..392058 | 390934..392058 | within | 0 |
Gene organization within MGE regions
Location: 369087..392058
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J97_RS01785 (I6J97_01785) | gspA | 369087..370556 (+) | 1470 | WP_000107592.1 | type II secretion system protein GspA | - |
| I6J97_RS01790 (I6J97_01790) | gspB | 370558..370977 (+) | 420 | WP_000461443.1 | putative general secretion pathway protein GspB | - |
| I6J97_RS01795 (I6J97_01795) | rpsJ | 371215..371526 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| I6J97_RS01800 (I6J97_01800) | rplC | 371559..372188 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| I6J97_RS01805 (I6J97_01805) | rplD | 372199..372804 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| I6J97_RS01810 (I6J97_01810) | rplW | 372801..373103 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| I6J97_RS01815 (I6J97_01815) | rplB | 373121..373942 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| I6J97_RS01820 (I6J97_01820) | rpsS | 373959..374237 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| I6J97_RS01825 (I6J97_01825) | rplV | 374252..374584 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| I6J97_RS01830 (I6J97_01830) | rpsC | 374602..375303 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| I6J97_RS01835 (I6J97_01835) | rplP | 375316..375726 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| I6J97_RS01840 (I6J97_01840) | rpmC | 375726..375917 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| I6J97_RS01845 (I6J97_01845) | rpsQ | 375917..376171 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| I6J97_RS01850 (I6J97_01850) | rplN | 376336..376707 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| I6J97_RS01855 (I6J97_01855) | rplX | 376718..377032 (+) | 315 | WP_000729186.1 | 50S ribosomal protein L24 | - |
| I6J97_RS01860 (I6J97_01860) | rplE | 377047..377586 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| I6J97_RS01865 (I6J97_01865) | rpsN | 377601..377906 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| I6J97_RS01870 (I6J97_01870) | rpsH | 377940..378332 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| I6J97_RS01875 (I6J97_01875) | rplF | 378345..378878 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| I6J97_RS01880 (I6J97_01880) | rplR | 378888..379241 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| I6J97_RS01885 (I6J97_01885) | rpsE | 379256..379759 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| I6J97_RS01890 (I6J97_01890) | rpmD | 379763..379942 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| I6J97_RS01895 (I6J97_01895) | rplO | 379946..380380 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| I6J97_RS01900 (I6J97_01900) | secY | 380388..381719 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| I6J97_RS01905 (I6J97_01905) | rpmJ | 381751..381867 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| I6J97_RS01910 (I6J97_01910) | rpsM | 382014..382370 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| I6J97_RS01915 (I6J97_01915) | rpsK | 382387..382776 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| I6J97_RS01920 (I6J97_01920) | rpsD | 382810..383430 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| I6J97_RS01925 (I6J97_01925) | rpoA | 383456..384445 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| I6J97_RS01930 (I6J97_01930) | rplQ | 384486..384869 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| I6J97_RS01935 (I6J97_01935) | yhdN | 384976..385344 (+) | 369 | WP_000266504.1 | DUF1992 domain-containing protein | - |
| I6J97_RS01940 (I6J97_01940) | zntR | 385355..385780 (+) | 426 | WP_000285610.1 | Zn(2+)-responsive transcriptional regulator | - |
| I6J97_RS01945 (I6J97_01945) | arfA | 385836..386054 (+) | 219 | WP_000092695.1 | alternative ribosome-rescue factor ArfA | - |
| I6J97_RS01950 (I6J97_01950) | mscL | 386051..386464 (-) | 414 | WP_000022450.1 | large-conductance mechanosensitive channel protein MscL | - |
| I6J97_RS01955 (I6J97_01955) | trkA | 386594..387970 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| I6J97_RS01960 (I6J97_01960) | rsmB | 387992..389281 (-) | 1290 | WP_000744767.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| I6J97_RS01965 (I6J97_01965) | fmt | 389333..390280 (-) | 948 | WP_000004421.1 | methionyl-tRNA formyltransferase | - |
| I6J97_RS01970 (I6J97_01970) | def | 390295..390804 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| I6J97_RS01975 (I6J97_01975) | dprA | 390934..392058 (+) | 1125 | WP_000228517.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 40910.86 Da Isoelectric Point: 6.0395
>NTDB_id=535310 I6J97_RS01975 WP_000228517.1 390934..392058(+) (dprA) [Escherichia coli strain FDAARGOS_1267]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=535310 I6J97_RS01975 WP_000228517.1 390934..392058(+) (dprA) [Escherichia coli strain FDAARGOS_1267]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Glaesserella parasuis strain SC1401 |
44.807 |
90.107 |
0.404 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.242 |
88.235 |
0.39 |