Detailed information NTG0053359

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: HMPREF1038_RS09115
• Genome accession: NC_018630
• Coordinates: 1709237..1710304 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae gamPNI0373
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1704237..1715304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF1038_RS09090 (HMPREF1038_01852)	treR	1704424..1705134 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
HMPREF1038_RS09095 (HMPREF1038_01853)	-	1705167..1705970 (-)	804	WP_014947348.1	ABC transporter ATP-binding protein	-
HMPREF1038_RS13265 (HMPREF1038_01854)	-	1705983..1706860 (-)	878	Protein_1739	ABC transporter permease	-
HMPREF1038_RS09105 (HMPREF1038_01856)	-	1706905..1707681 (-)	777	Protein_1740	ABC transporter substrate-binding protein	-
HMPREF1038_RS09110 (HMPREF1038_01859)	amiF	1708300..1709226 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
HMPREF1038_RS09115 (HMPREF1038_01860)	amiE	1709237..1710304 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
HMPREF1038_RS09120 (HMPREF1038_01861)	amiD	1710313..1711239 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
HMPREF1038_RS09125 (HMPREF1038_01862)	amiC	1711239..1712735 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
HMPREF1038_RS09130 (HMPREF1038_01863)	amiA3	1712802..1714781 (-)	1980	WP_000742229.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=53359 HMPREF1038_RS09115 WP_000159554.1 1709237..1710304(-) (amiE) [Streptococcus pneumoniae gamPNI0373]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=53359 HMPREF1038_RS09115 WP_000159554.1 1709237..1710304(-) (amiE) [Streptococcus pneumoniae gamPNI0373]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATTCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541