Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   JQR77_RS07265 Genome accession   NZ_CP069275
Coordinates   1421294..1421989 (-) Length   231 a.a.
NCBI ID   WP_023909867.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EG007     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1416294..1426989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JQR77_RS07250 (JQR77_07270) - 1417105..1417650 (-) 546 WP_011681493.1 GNAT family N-acetyltransferase -
  JQR77_RS07255 (JQR77_07275) - 1417716..1418978 (-) 1263 WP_011681494.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  JQR77_RS07260 (JQR77_07280) - 1419064..1421304 (-) 2241 WP_011681495.1 DNA internalization-related competence protein ComEC/Rec2 -
  JQR77_RS07265 (JQR77_07285) comEA 1421294..1421989 (-) 696 WP_023909867.1 helix-hairpin-helix domain-containing protein Machinery gene
  JQR77_RS07270 (JQR77_07290) - 1422359..1423093 (+) 735 WP_253269287.1 Rgg/GadR/MutR family transcriptional regulator -
  JQR77_RS07275 (JQR77_07295) - 1423580..1424650 (+) 1071 WP_041829155.1 radical SAM protein -
  JQR77_RS07280 (JQR77_07300) - 1424640..1425725 (+) 1086 WP_023909868.1 radical SAM/SPASM domain-containing protein -
  JQR77_RS07285 (JQR77_07305) - 1425712..1425975 (+) 264 WP_014621867.1 hypothetical protein -
  JQR77_RS07290 (JQR77_07310) - 1425968..1426861 (+) 894 WP_023909869.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24539.52 Da        Isoelectric Point: 4.7259

>NTDB_id=533220 JQR77_RS07265 WP_023909867.1 1421294..1421989(-) (comEA) [Streptococcus thermophilus strain EG007]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQRSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=533220 JQR77_RS07265 WP_023909867.1 1421294..1421989(-) (comEA) [Streptococcus thermophilus strain EG007]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGATCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.567

100

0.996
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.175

99.134

0.398
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.281

98.701

0.368