Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   JM964_RS06275 Genome accession   NZ_CP068708
Coordinates   1289474..1291711 (-) Length   745 a.a.
NCBI ID   WP_202847476.1    Uniprot ID   -
Organism   Streptococcus suis strain ID33329     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1284474..1296711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM964_RS06260 (JM964_06260) - 1285341..1287365 (-) 2025 WP_202847474.1 surface-anchored 5'-nucleotidase -
  JM964_RS06265 (JM964_06265) sodA 1287629..1288234 (-) 606 WP_013730459.1 superoxide dismutase SodA -
  JM964_RS06270 (JM964_06270) holA 1288347..1289378 (-) 1032 WP_202847475.1 DNA polymerase III subunit delta -
  JM964_RS06275 (JM964_06275) comEC/celB 1289474..1291711 (-) 2238 WP_202847476.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  JM964_RS06280 (JM964_06280) - 1291695..1292357 (-) 663 WP_202847477.1 helix-hairpin-helix domain-containing protein -
  JM964_RS06285 (JM964_06285) - 1292425..1293171 (-) 747 WP_014735985.1 lysophospholipid acyltransferase family protein -
  JM964_RS06290 (JM964_06290) - 1293317..1294762 (+) 1446 WP_044674357.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  JM964_RS06295 (JM964_06295) - 1295062..1295847 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83971.93 Da        Isoelectric Point: 7.1967

>NTDB_id=530557 JM964_RS06275 WP_202847476.1 1289474..1291711(-) (comEC/celB) [Streptococcus suis strain ID33329]
MSRLSKLPCQPIHLALLAVAAYFAVHSFSLLTMGLLSLLLVVFGVRQGKTVFIKTLPLLTLCGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTDLVRLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSLVYAGLTGFSVSVVRSLIQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYALLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLIKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELFLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVKIGRIVVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=530557 JM964_RS06275 WP_202847476.1 1289474..1291711(-) (comEC/celB) [Streptococcus suis strain ID33329]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATGGGCCTGCTGAGTCTGTTACTAGTAGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTTATCA
AAACGCTGCCGCTTCTAACCCTATGTGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTGTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGTTGACAGATTTGG
TCCGGCTTGAAGTGGAAGCAGAAGTCAGCCTGCCAGCTGGTCAACGCAATTTCAAGGGCTTTGACTATCAAGCCTATCTG
AAAACGCAGGGGATTTACCGGACAGTTAAGCTAACAGCGATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCCCTTGTTTATGCTGGTTTGACAGGCTTTTCGGTGTCGGTGGTGCGGTCACTTA
TCCAAAAAATTCTGGGCAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACAGTCTTTGTCTGTTTGCTGATTCTG
CCCCGATTTCTTTTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTCTTTTGCTGACGGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTTGGAATTTTGCCGGTGCTTATGACCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACCTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGCTTGTCGGTC
ATTTTTCTCCTCTCACCCTTGATCAAGATTACTTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGTTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCTTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGATACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCGAAGCAGGTGAAAATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCTTGCCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAACCTGCCAGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCAGGAGAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAGTAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(30-175)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.778

99.732

0.546
  comEC/celB Streptococcus mitis NCTC 12261

53.93

99.06

0.534
  comEC/celB Streptococcus pneumoniae TIGR4

53.045

99.195

0.526
  comEC/celB Streptococcus pneumoniae Rx1

52.774

99.195

0.523
  comEC/celB Streptococcus pneumoniae D39

52.774

99.195

0.523
  comEC/celB Streptococcus pneumoniae R6

52.774

99.195

0.523
  comEC Lactococcus lactis subsp. cremoris KW2

49.132

100

0.494