Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6J14_RS06220 Genome accession   NZ_CP068057
Coordinates   1239578..1240264 (-) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1234578..1245264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS06200 (I6J14_06200) dnaI 1235307..1236209 (-) 903 WP_115252619.1 primosomal protein DnaI -
  I6J14_RS06205 (I6J14_06205) - 1236210..1237388 (-) 1179 WP_115252618.1 DnaD domain protein -
  I6J14_RS06210 (I6J14_06210) nrdR 1237372..1237866 (-) 495 WP_003049740.1 transcriptional regulator NrdR -
  I6J14_RS06215 (I6J14_06215) - 1238073..1239572 (-) 1500 WP_115252617.1 HAMP domain-containing histidine kinase -
  I6J14_RS06220 (I6J14_06220) covR 1239578..1240264 (-) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  I6J14_RS06225 (I6J14_06225) - 1240535..1241068 (-) 534 WP_174221706.1 DUF177 domain-containing protein -
  I6J14_RS06230 (I6J14_06230) htpX 1241335..1242228 (-) 894 WP_003049732.1 zinc metalloprotease HtpX -
  I6J14_RS06235 (I6J14_06235) - 1242273..1242830 (-) 558 WP_003049731.1 LemA family protein -
  I6J14_RS06240 (I6J14_06240) rsmG 1242983..1243696 (+) 714 WP_115246663.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6J14_RS06245 (I6J14_06245) ktrB 1243780..1245156 (+) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=526727 I6J14_RS06220 WP_003049736.1 1239578..1240264(-) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=526727 I6J14_RS06220 WP_003049736.1 1239578..1240264(-) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
CGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTAGAAACTGCCTTAGAAAAGGATTTTGACTTAATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATTATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGGTTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCAATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGGTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425