Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   JJN14_RS09835 Genome accession   NZ_CP067992
Coordinates   1999380..2000678 (-) Length   432 a.a.
NCBI ID   WP_201058558.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1994380..2005678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS09815 (JJN14_09815) rplI 1995535..1995987 (-) 453 WP_060627336.1 50S ribosomal protein L9 -
  JJN14_RS09820 (JJN14_09820) - 1995984..1997957 (-) 1974 WP_201058556.1 DHH family phosphoesterase -
  JJN14_RS09825 (JJN14_09825) hpf 1998093..1998641 (-) 549 WP_004255322.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  JJN14_RS09830 (JJN14_09830) comFC/cflB 1998721..1999383 (-) 663 WP_201058557.1 ComF family protein Machinery gene
  JJN14_RS09835 (JJN14_09835) comFA/cflA 1999380..2000678 (-) 1299 WP_201058558.1 DEAD/DEAH box helicase Machinery gene
  JJN14_RS09840 (JJN14_09840) - 2000735..2001370 (+) 636 WP_033682509.1 YigZ family protein -
  JJN14_RS09845 (JJN14_09845) - 2001386..2001829 (+) 444 WP_061088574.1 PH domain-containing protein -
  JJN14_RS09850 (JJN14_09850) cysK 2001926..2002852 (+) 927 WP_201058559.1 cysteine synthase A -
  JJN14_RS09855 (JJN14_09855) tsf 2002978..2004018 (-) 1041 WP_033682512.1 translation elongation factor Ts -
  JJN14_RS09860 (JJN14_09860) rpsB 2004097..2004876 (-) 780 WP_000268469.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49646.43 Da        Isoelectric Point: 8.4400

>NTDB_id=526187 JJN14_RS09835 WP_201058558.1 1999380..2000678(-) (comFA/cflA) [Streptococcus mitis strain S022-V7-A3]
MKVNPNYLGRLFTENELTEEERKLAENIPAMRKEKGKFFCQRCNSTILEEWYLPIGAYYCRECLIMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLIQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQDDFACEISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKKNGLRIFLTATST
DELDRKVRIGELKRLSLPRRFHGNPLIIPKPVWLSDFNRYLDKNRLSPKLKTYIEKQRKTGYHLLIFASEIKKGEQLKEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=526187 JJN14_RS09835 WP_201058558.1 1999380..2000678(-) (comFA/cflA) [Streptococcus mitis strain S022-V7-A3]
ATGAAAGTAAATCCAAATTATCTCGGTCGGTTGTTTACTGAGAATGAATTAACAGAAGAGGAACGTAAGTTGGCAGAGAA
CATTCCAGCAATGAGAAAGGAGAAGGGAAAATTTTTCTGTCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTAC
CTATCGGTGCTTATTATTGTCGGGAGTGCTTAATTATGAAGCGAGTTAGGAGTGATCAAGCTTTATACTATTTCCCACAG
GAGGATTTTCCGAAACAAGATGTTCTTAAATGGCGTGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGATTGAT
TCAAGCAGTAGATAAGCAAGAACCAACCTTGGTACATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TAGCTAAAGTGATCAATGCGGGTGGTGCAGTATGCTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGA
CTGCAAGATGATTTTGCTTGCGAGATATCTTTACTACACGGAGAATCAGAGCCGTATTTTCGAACACCACTAGTTGTTGC
GACGACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGAAGAATGGCTTGAGAATCTTTTTAACAGCAACTTCTACC
GATGAGTTAGATAGGAAGGTTCGCATCGGAGAATTAAAACGATTGAGTTTGCCTAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAGCCTGTCTGGTTATCGGATTTTAATCGCTATTTGGATAAGAATCGTTTGTCACCAAAGCTAAAGACTTATA
TTGAGAAACAGAGAAAGACAGGCTATCACTTACTCATTTTTGCTTCAGAAATTAAGAAAGGAGAGCAACTAAAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAAGATAGATTAGAGCAGGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTTG
TAGTAGAAGCCAACCATCGTCTGTTTACCAAATCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGACGGGTTAAATGCTTCAATCAAAAAGGCAATTAAGGAAATTCAACAGATGAA
TAAGGAGGCGGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

93.981

100

0.94
  comFA/cflA Streptococcus pneumoniae Rx1

93.981

100

0.94
  comFA/cflA Streptococcus pneumoniae D39

93.981

100

0.94
  comFA/cflA Streptococcus pneumoniae R6

93.981

100

0.94
  comFA/cflA Streptococcus mitis NCTC 12261

93.981

100

0.94
  comFA/cflA Streptococcus pneumoniae TIGR4

93.75

100

0.938
  comFA Lactococcus lactis subsp. cremoris KW2

50

99.074

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

38.391

100

0.387
  comFA Bacillus subtilis subsp. subtilis str. 168

39.036

96.065

0.375