Detailed information NTG0526145

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: JJN14_RS02565
• Genome accession: NZ_CP067992
• Coordinates: 490530..491189 (-)
• Length: 219 a.a.
• NCBI ID: WP_201058816.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain S022-V7-A3
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 485530..496189

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JJN14_RS02535 (JJN14_02535)	-	485657..486223 (+)	567	WP_042900462.1	aminodeoxychorismate/anthranilate synthase component II	-
JJN14_RS02540 (JJN14_02540)	trpD	486234..487238 (+)	1005	WP_201058812.1	anthranilate phosphoribosyltransferase	-
JJN14_RS02545 (JJN14_02545)	trpC	487235..488002 (+)	768	WP_201058813.1	indole-3-glycerol phosphate synthase TrpC	-
JJN14_RS02550 (JJN14_02550)	-	487989..488588 (+)	600	WP_201058814.1	phosphoribosylanthranilate isomerase	-
JJN14_RS02555 (JJN14_02555)	trpB	488566..489789 (+)	1224	WP_000331265.1	tryptophan synthase subunit beta	-
JJN14_RS02560 (JJN14_02560)	trpA	489782..490558 (+)	777	WP_201058815.1	tryptophan synthase subunit alpha	-
JJN14_RS02565 (JJN14_02565)	cclA/cilC	490530..491189 (-)	660	WP_201058816.1	prepilin peptidase	Machinery gene
JJN14_RS02570 (JJN14_02570)	-	491259..491714 (+)	456	WP_201058817.1	GNAT family N-acetyltransferase	-
JJN14_RS10335 (JJN14_02575)	-	491732..492024 (+)	293	Protein_449	transposase	-
JJN14_RS02580 (JJN14_02580)	-	492134..492337 (-)	204	WP_201058818.1	CsbD family protein	-
JJN14_RS02585 (JJN14_02585)	-	492368..492976 (-)	609	WP_201058819.1	Asp23/Gls24 family envelope stress response protein	-
JJN14_RS02590 (JJN14_02590)	-	493007..493177 (-)	171	WP_000455064.1	DUF2273 domain-containing protein	-
JJN14_RS02595 (JJN14_02595)	amaP	493189..493761 (-)	573	WP_201058820.1	alkaline shock response membrane anchor protein AmaP	-
JJN14_RS02600 (JJN14_02600)	-	493839..494074 (-)	236	Protein_454	GlsB/YeaQ/YmgE family stress response membrane protein	-
JJN14_RS02605 (JJN14_02605)	mgaSpn	494450..495928 (+)	1479	WP_201058822.1	virulence factor transcriptional regulator MgaSpn	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24654.76 Da
• Isoelectric Point: 7.2760

>NTDB_id=526145 JJN14_RS02565 WP_201058816.1 490530..491189(-) (cclA/cilC) [Streptococcus mitis strain S022-V7-A3]
MINIYFFLVGSILASFLGLVIDRFPEQSIISPASHCDSCQTPLRPLDLIPILSQVFNHFRCRYCKAPYPVWYALLELGLG
LIFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILMASSGWNLVMVFFLALGILAHFIDIRMGAGDFL
FLASCALAFSATELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=526145 JJN14_RS02565 WP_201058816.1 490530..491189(-) (cclA/cilC) [Streptococcus mitis strain S022-V7-A3]
ATGATTAATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGCCCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTTTTTAATCACTTTCGCTGTCGCTACTGCAAGGCTCCTTATCCCGTCTGGTATGCCCTTTTGGAACTAGGCTTAGGA
CTCATATTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCGGGTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTTCTTCCTTGCCCTTGGAATTTTAGCTCATTTTATTGATATTCGCATGGGCGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCTCTCGCCTTTAGCGCGACCGAATTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGCATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae Rx1	93.151	100	0.932
cclA/cilC	Streptococcus pneumoniae D39	93.151	100	0.932
cclA/cilC	Streptococcus pneumoniae R6	93.151	100	0.932
cclA/cilC	Streptococcus pneumoniae TIGR4	89.954	100	0.9
cclA/cilC	Streptococcus mitis NCTC 12261	87.671	100	0.877