Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   JGZ18_RS00245 Genome accession   NZ_CP066714
Coordinates   50120..51748 (-) Length   542 a.a.
NCBI ID   WP_001186596.1    Uniprot ID   -
Organism   Staphylococcus pseudintermedius strain DSP021     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 38310..53115 50120..51748 within 0


Gene organization within MGE regions


Location: 38310..53115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGZ18_RS00175 (JGZ18_00175) mecA 38310..40319 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  JGZ18_RS00180 (JGZ18_00180) mecR1 40416..42173 (+) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  JGZ18_RS00185 (JGZ18_00185) mecI 42173..42544 (+) 372 WP_025904161.1 mecA-type methicillin resistance repressor MecI -
  JGZ18_RS00190 (JGZ18_00190) psm-mec 42629..42697 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  JGZ18_RS00195 (JGZ18_00195) - 43056..44164 (+) 1109 Protein_37 ROK family transcriptional regulator -
  JGZ18_RS00200 (JGZ18_00200) cstB 44278..45612 (-) 1335 Protein_38 persulfide dioxygenase-sulfurtransferase CstB -
  JGZ18_RS00205 (JGZ18_00205) - 45645..46709 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  JGZ18_RS00210 (JGZ18_00210) cstR 46845..47105 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  JGZ18_RS00215 (JGZ18_00215) - 47105..47743 (+) 639 Protein_41 sulfite exporter TauE/SafE family protein -
  JGZ18_RS13610 (JGZ18_00220) - 47797..48162 (-) 366 Protein_42 JAB domain-containing protein -
  JGZ18_RS00225 (JGZ18_00225) - 48155..48361 (-) 207 WP_001077283.1 hypothetical protein -
  JGZ18_RS00230 (JGZ18_00230) - 48363..48884 (-) 522 WP_000836008.1 DUF1643 domain-containing protein -
  JGZ18_RS00235 (JGZ18_00235) - 48903..49214 (-) 312 WP_000833212.1 DUF960 family protein -
  JGZ18_RS00240 (JGZ18_00240) - 49299..49649 (-) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  JGZ18_RS00245 (JGZ18_00245) ccrB 50120..51748 (-) 1629 WP_001186596.1 recombinase family protein Machinery gene
  JGZ18_RS00250 (JGZ18_00250) ccrA 51769..53115 (-) 1347 WP_000816499.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62274.15 Da        Isoelectric Point: 9.7334

>NTDB_id=521952 JGZ18_RS00245 WP_001186596.1 50120..51748(-) (ccrB) [Staphylococcus pseudintermedius strain DSP021]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=521952 JGZ18_RS00245 WP_001186596.1 50120..51748(-) (ccrB) [Staphylococcus pseudintermedius strain DSP021]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.531

100

0.865