Detailed information NTG0052147

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LPO_RS13465
• Genome accession: NC_018139
• Coordinates: 2986978..2988063 (+)
• Length: 361 a.a.
• NCBI ID: WP_014842656.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2981978..2993063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPO_RS13440 (LPO_2867)	-	2982371..2983120 (-)	750	WP_014842652.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
LPO_RS13445 (LPO_2868)	rsmB	2983117..2984400 (-)	1284	WP_014842653.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LPO_RS13450 (LPO_2869)	fmt	2984397..2985341 (-)	945	WP_014842654.1	methionyl-tRNA formyltransferase	-
LPO_RS13455 (LPO_2870)	def	2985338..2985850 (-)	513	WP_010948295.1	peptide deformylase	-
LPO_RS13460 (LPO_2871)	-	2985944..2986981 (+)	1038	WP_014842655.1	LysM peptidoglycan-binding domain-containing protein	-
LPO_RS13465 (LPO_2872)	dprA	2986978..2988063 (+)	1086	WP_014842656.1	DNA-processing protein DprA	Machinery gene
LPO_RS13470 (LPO_2873)	-	2988053..2988490 (+)	438	WP_011947522.1	DUF494 family protein	-
LPO_RS13475 (LPO_2874)	topA	2988570..2990849 (+)	2280	WP_014842657.1	type I DNA topoisomerase	-
LPO_RS13480 (LPO_2875)	-	2991060..2993033 (-)	1974	WP_014842658.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39569.74 Da
• Isoelectric Point: 7.0520

>NTDB_id=52147 LPO_RS13465 WP_014842656.1 2986978..2988063(+) (dprA) [Legionella pneumophila subsp. pneumophila]
MNNLQPLLALNRMKKIGPRTVLKLQKRWPDLNLMFQLSSVDLEEAGLPSWLVQTIKNFDPDFIKTDLDWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSALTQPNLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEGGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVIAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=52147 LPO_RS13465 WP_014842656.1 2986978..2988063(+) (dprA) [Legionella pneumophila subsp. pneumophila]
ATGAATAATCTGCAACCCCTCCTCGCCTTAAACAGGATGAAAAAAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCCAGTGTTGATCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGTACAAA
CCATAAAAAATTTTGATCCGGACTTTATAAAAACTGACTTGGACTGGTTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCTGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCCTTGACACAACCCAACCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGAGCATTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCCTTGGGAATTGATGCTCACGCTCATTTAGGCTGT
CTGGAAGGAGGCGGCAAAACGATAGCGGTCTTAGGTACCGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCTATTCCCGGATCGATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAGCAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATTGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACGACTATC
GATCAAATCATTGATCGTAGCGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATAGCAGTGCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	98.892	100	0.989
dprA	Vibrio campbellii strain DS40M4	44.722	99.723	0.446
dprA	Vibrio cholerae strain A1552	42.895	100	0.443
dprA	Glaesserella parasuis strain SC1401	39.2	100	0.407
dprA	Haemophilus influenzae Rd KW20	46.048	80.609	0.371