Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMUGS5_RS08630 Genome accession   NC_018089
Coordinates   1784625..1785317 (-) Length   230 a.a.
NCBI ID   WP_014835042.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1779625..1790317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS08605 (SMUGS5_08570) - 1779687..1780313 (-) 627 WP_002265453.1 hypothetical protein -
  SMUGS5_RS08610 (SMUGS5_08575) der 1780388..1781698 (-) 1311 WP_002280559.1 ribosome biogenesis GTPase Der -
  SMUGS5_RS08615 (SMUGS5_08580) dnaI 1781711..1782610 (-) 900 WP_002267936.1 primosomal protein DnaI -
  SMUGS5_RS08620 - 1782611..1783778 (-) 1168 Protein_1676 DnaD domain protein -
  SMUGS5_RS08625 (SMUGS5_08595) nrdR 1783765..1784256 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  SMUGS5_RS08630 (SMUGS5_08600) covR 1784625..1785317 (-) 693 WP_014835042.1 response regulator GcrR Regulator
  SMUGS5_RS08635 (SMUGS5_08605) - 1785673..1786209 (-) 537 WP_002262122.1 DUF177 domain-containing protein -
  SMUGS5_RS08640 (SMUGS5_08610) - 1786202..1786777 (-) 576 WP_002265122.1 TetR/AcrR family transcriptional regulator -
  SMUGS5_RS08645 (SMUGS5_08615) - 1786885..1787592 (+) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  SMUGS5_RS08650 (SMUGS5_08620) - 1787594..1790206 (+) 2613 WP_002263841.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26686.67 Da        Isoelectric Point: 4.8849

>NTDB_id=52055 SMUGS5_RS08630 WP_014835042.1 1784625..1785317(-) (covR) [Streptococcus mutans GS-5]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYICYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=52055 SMUGS5_RS08630 WP_014835042.1 1784625..1785317(-) (covR) [Streptococcus mutans GS-5]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTTATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAGACTAATGTTGTCGATGTTTATATTTGCTATCTTCGTGGGAAGATTGATGTTCCTGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

77.632

99.13

0.77
  covR Lactococcus lactis subsp. lactis strain DGCC12653

62.996

98.696

0.622
  vicR Streptococcus mutans UA159

42.424

100

0.426
  micA Streptococcus pneumoniae Cp1015

41.202

100

0.417

Multiple sequence alignment