Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   JDY60_RS04465 Genome accession   NZ_CP066172
Coordinates   924284..925621 (-) Length   445 a.a.
NCBI ID   WP_200371549.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 919284..930621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS04440 (JDY60_04440) rpiA 919956..920639 (-) 684 WP_200371545.1 ribose-5-phosphate isomerase RpiA -
  JDY60_RS04445 (JDY60_04445) - 920745..921674 (-) 930 WP_125456908.1 peptidase U32 family protein -
  JDY60_RS04450 (JDY60_04450) - 921800..922480 (-) 681 WP_000209231.1 ABC transporter ATP-binding protein -
  JDY60_RS04455 (JDY60_04455) - 922494..923549 (-) 1056 WP_049479725.1 ABC transporter permease -
  JDY60_RS04460 (JDY60_04460) - 923935..924219 (+) 285 WP_200371547.1 DUF3270 domain-containing protein -
  JDY60_RS04465 (JDY60_04465) ciaH 924284..925621 (-) 1338 WP_200371549.1 cell wall metabolism sensor histidine kinase WalK Regulator
  JDY60_RS04470 (JDY60_04470) ciaR 925611..926285 (-) 675 WP_000590635.1 two-component system response regulator CiaR Regulator
  JDY60_RS04475 (JDY60_04475) - 926394..928940 (-) 2547 WP_200371550.1 M1 family metallopeptidase -
  JDY60_RS04480 (JDY60_04480) - 929061..929501 (-) 441 WP_000188825.1 ASCH domain-containing protein -
  JDY60_RS04485 (JDY60_04485) - 929498..930346 (-) 849 WP_200371552.1 putative PEP-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 50815.53 Da        Isoelectric Point: 9.6556

>NTDB_id=518046 JDY60_RS04465 WP_200371549.1 924284..925621(-) (ciaH) [Streptococcus oralis strain SF100]
MFNKLKKTWYADDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLQALSSSPQAVIQLALNRATEEVKDIQPAT
ADASKAEIKPNVSSNTEVLLFDKDFNQLLLGNRFLGLDKIKLDKKELNHIRQIQVVNSYGQEETYRMILMETNSSSVSSN
VKYAAVLINTSQLEQISQNHEHLIVVVMASFWLLSLIASVYLARVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLE
NLFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEIAEVSPQFFKTTFANYELIASENDRVFNYENRI
YRPFMTDQLLLKQLMTILFDNAIKYTEEDGKIEFVVYATDRHLYLTVTDNGIGISAADKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALRGTITVKDNKPRGTIFEVKIAIQTPSKRKNK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=518046 JDY60_RS04465 WP_200371549.1 924284..925621(-) (ciaH) [Streptococcus oralis strain SF100]
ATGTTCAATAAACTAAAAAAAACATGGTATGCGGATGATTTCAGCTATTTCATTCGAAACTTTGGAGTGTTCACCCTGAT
CTTCTCTGCTATGACCTTGATTATCCTCCAGGTCATGCACTCGAGTCTCTACACTTCTGTAGATGAAAAACTCCAAGCCC
TTAGTAGCAGTCCCCAAGCGGTTATCCAGTTAGCCCTGAATCGGGCCACCGAAGAGGTCAAGGATATTCAACCCGCAACT
GCGGATGCCAGCAAGGCTGAAATCAAGCCCAATGTCAGCTCCAATACGGAAGTCTTGCTCTTTGACAAGGATTTTAACCA
ACTCTTACTGGGCAATCGCTTTTTAGGCTTGGACAAGATCAAGCTGGACAAAAAGGAGTTGAATCACATTCGGCAAATCC
AAGTTGTCAATAGCTACGGTCAGGAAGAAACCTATCGGATGATTTTGATGGAAACCAATTCTTCCTCCGTATCAAGCAAT
GTCAAATATGCGGCAGTTTTAATTAATACCAGCCAGCTTGAGCAAATCAGTCAAAACCACGAGCATTTAATTGTTGTAGT
CATGGCTAGTTTCTGGCTCCTGTCTTTAATTGCCAGTGTTTATTTGGCACGTGTCAGTGTCAAACCCTTACTGGAAAGTA
TGCAAAAGCAGAAGTCTTTTGTTGAAAATGCCAGTCACGAACTGAGAACGCCTTTGGCCGTTTTACAAAATCGTTTAGAA
AATCTCTTTCGAAAACCAGAGGCAACAATCATGGAATCCAGCGAAAGTATCGCTTCCAGTCTTGAAGAAGTTCGCAACAT
GCGCTTCCTTACGACCAATCTTCTCAACCTTGCGCGTCGAGATGATGGAATCAAACCAGAAATAGCAGAAGTATCACCAC
AGTTCTTTAAGACGACCTTTGCCAACTATGAGTTGATCGCTTCTGAAAATGATCGTGTTTTCAACTATGAAAATCGAATT
TATCGTCCATTCATGACCGATCAGTTGCTCTTAAAACAACTCATGACCATCCTGTTTGATAATGCCATCAAGTATACCGA
AGAAGATGGGAAAATTGAGTTTGTAGTTTATGCTACAGATCGCCATCTCTATCTTACAGTAACGGATAATGGAATTGGAA
TCTCAGCTGCTGACAAGAAGAAAATCTTTGACCGTTTTTACCGTGTAGACAAAGCGAGAACCCGTCAGAAAGGTGGCTTT
GGTCTTGGACTATCTTTGGCCAAGCAAATCGTAGATGCCTTACGAGGAACGATTACCGTAAAAGATAACAAACCTAGAGG
AACAATTTTTGAAGTTAAGATTGCCATCCAGACTCCCTCGAAACGTAAGAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

84.876

99.551

0.845
  ciaH Streptococcus pneumoniae D39

84.876

99.551

0.845
  ciaH Streptococcus pneumoniae R6

84.876

99.551

0.845
  ciaH Streptococcus pneumoniae TIGR4

84.876

99.551

0.845
  ciaH Streptococcus mutans UA159

55.023

98.427

0.542