Detailed information NTG0517354

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: I6I02_RS03630
• Genome accession: NZ_CP066093
• Coordinates: 830131..831546 (+)
• Length: 471 a.a.
• NCBI ID: WP_198463843.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 825131..836546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS03605 (I6I02_03605)	-	825582..826154 (-)	573	WP_022496698.1	ECF transporter S component	-
I6I02_RS03610 (I6I02_03610)	coaC	826183..826728 (-)	546	WP_198463840.1	phosphopantothenoylcysteine decarboxylase	-
I6I02_RS03615 (I6I02_03615)	-	826721..827404 (-)	684	WP_198463841.1	phosphopantothenate--cysteine ligase	-
I6I02_RS03620 (I6I02_03620)	-	827598..829268 (+)	1671	WP_198463842.1	formate--tetrahydrofolate ligase	-
I6I02_RS03625 (I6I02_03625)	ciaR	829467..830141 (+)	675	WP_002891134.1	response regulator transcription factor	Regulator
I6I02_RS03630 (I6I02_03630)	ciaH	830131..831546 (+)	1416	WP_198463843.1	sensor histidine kinase	Regulator
I6I02_RS03635 (I6I02_03635)	rpsT	831624..831860 (-)	237	WP_004182129.1	30S ribosomal protein S20	-
I6I02_RS03640 (I6I02_03640)	coaA	831930..832850 (-)	921	WP_013990467.1	type I pantothenate kinase	-
I6I02_RS03645 (I6I02_03645)	-	832963..833553 (+)	591	WP_013990468.1	class I SAM-dependent methyltransferase	-
I6I02_RS03650 (I6I02_03650)	-	833550..834827 (+)	1278	WP_013990469.1	pyrimidine-nucleoside phosphorylase	-
I6I02_RS03655 (I6I02_03655)	deoC	834861..835523 (+)	663	WP_013990470.1	deoxyribose-phosphate aldolase	-
I6I02_RS03660 (I6I02_03660)	-	835510..835908 (+)	399	WP_037600754.1	cytidine deaminase	-

Sequence

Protein

• Length: 471 a.a.
• Molecular weight: 53486.26 Da
• Isoelectric Point: 8.7661

>NTDB_id=517354 I6I02_RS03630 WP_198463843.1 830131..831546(+) (ciaH) [Streptococcus salivarius strain FDAARGOS_1045]
MLTKFFNYLFRRMKSEGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide

• Length: 1416 bp

>NTDB_id=517354 I6I02_RS03630 WP_198463843.1 830131..831546(+) (ciaH) [Streptococcus salivarius strain FDAARGOS_1045]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATGAAGTCAGAAGGATTTAAGTCTTTCATTCATTTCTTTGCGAC
TTTTTCTGGTATTTTCCTTATCATGACAGTCATGATTTTGCAGATTCTGAGTTACGGTGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCGACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACCTCTGAG
GTAGATCAAAATAATACGACAACCATTTATCAGGCTTATGATACTAAAGGGTCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGCGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACCGGAGTTTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (361-468)

• His Kinase A (phospho-acceptor) domain (HisKA) (252-317)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	56.087	97.665	0.548
ciaH	Streptococcus pneumoniae Rx1	50	98.514	0.493
ciaH	Streptococcus pneumoniae D39	50	98.514	0.493
ciaH	Streptococcus pneumoniae R6	50	98.514	0.493
ciaH	Streptococcus pneumoniae TIGR4	50	98.514	0.493