Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6H73_RS01630 Genome accession   NZ_CP066073
Coordinates   316444..317130 (+) Length   228 a.a.
NCBI ID   WP_003059028.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 311444..322130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS01605 (I6H73_01605) ktrB 311551..312927 (-) 1377 WP_003059011.1 potassium uptake transporter channel subunit KtrB -
  I6H73_RS01610 (I6H73_01610) rsmG 313011..313724 (-) 714 WP_003058986.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6H73_RS01615 (I6H73_01615) - 313877..314434 (+) 558 WP_003058947.1 LemA family protein -
  I6H73_RS01620 (I6H73_01620) htpX 314481..315374 (+) 894 WP_003059035.1 zinc metalloprotease HtpX -
  I6H73_RS01625 (I6H73_01625) - 315641..316174 (+) 534 WP_003058949.1 DUF177 domain-containing protein -
  I6H73_RS01630 (I6H73_01630) covR 316444..317130 (+) 687 WP_003059028.1 two-component system response regulator CovR Regulator
  I6H73_RS01635 (I6H73_01635) - 317136..318635 (+) 1500 WP_003058944.1 HAMP domain-containing histidine kinase -
  I6H73_RS01640 (I6H73_01640) nrdR 318841..319335 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  I6H73_RS01645 (I6H73_01645) - 319319..320497 (+) 1179 WP_012766597.1 DnaD domain protein -
  I6H73_RS01650 (I6H73_01650) dnaI 320498..321400 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26514.51 Da        Isoelectric Point: 4.5899

>NTDB_id=517167 I6H73_RS01630 WP_003059028.1 316444..317130(+) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKCEY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=517167 I6H73_RS01630 WP_003059028.1 316444..317130(+) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAATGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

81.659

100

0.82
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.421