Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6H74_RS10475 Genome accession   NZ_CP066069
Coordinates   2109988..2110683 (-) Length   231 a.a.
NCBI ID   WP_115256761.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2104988..2115683
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS10455 (I6H74_10450) dnaI 2105718..2106620 (-) 903 WP_003058998.1 primosomal protein DnaI -
  I6H74_RS10460 (I6H74_10455) - 2106621..2107799 (-) 1179 WP_115256762.1 DnaD domain protein -
  I6H74_RS10465 (I6H74_10460) nrdR 2107783..2108277 (-) 495 WP_003049740.1 transcriptional regulator NrdR -
  I6H74_RS10470 (I6H74_10465) - 2108483..2109982 (-) 1500 WP_198455555.1 HAMP domain-containing histidine kinase -
  I6H74_RS10475 (I6H74_10470) covR 2109988..2110683 (-) 696 WP_115256761.1 two-component system response regulator CovR Regulator
  I6H74_RS10480 (I6H74_10475) - 2110953..2111486 (-) 534 WP_115256760.1 YceD family protein -
  I6H74_RS10485 (I6H74_10480) htpX 2111753..2112646 (-) 894 WP_003059035.1 zinc metalloprotease HtpX -
  I6H74_RS10490 (I6H74_10485) - 2112693..2113250 (-) 558 WP_003058947.1 LemA family protein -
  I6H74_RS10495 (I6H74_10490) rsmG 2113403..2114116 (+) 714 WP_003058986.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6H74_RS10500 (I6H74_10495) ktrB 2114200..2115576 (+) 1377 WP_115256759.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26840.85 Da        Isoelectric Point: 4.6541

>NTDB_id=517124 I6H74_RS10475 WP_115256761.1 2109988..2110683(-) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVSSVNRGDDEISLTK
REYDLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=517124 I6H74_RS10475 WP_115256761.1 2109988..2110683(-) (covR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAA
CGTGAATATGATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTG
GAAATACGATGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTA
AGGAGTCTTATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

81.034

100

0.814
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.522

99.567

0.662
  vicR Streptococcus mutans UA159

44.017

100

0.446
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.42