Detailed information NTG0051702

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: KW2_RS11285
• Genome accession: NC_022369
• Coordinates: 2344480..2347002 (-)
• Length: 840 a.a.
• NCBI ID: WP_021038001.1
• Uniprot ID: -
• Organism: Lactococcus cremoris subsp. cremoris KW2
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2339480..2352002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KW2_RS11265 (kw2_2269)	ruvB	2339782..2340783 (-)	1002	WP_014573419.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
KW2_RS11270 (kw2_2270)	ruvA	2340930..2341523 (-)	594	WP_021037998.1	Holliday junction branch migration protein RuvA	Machinery gene
KW2_RS11275 (kw2_2271)	hexB	2341575..2343545 (-)	1971	WP_021037999.1	DNA mismatch repair endonuclease MutL	Machinery gene
KW2_RS11280 (kw2_2272)	-	2343675..2344370 (-)	696	WP_021038000.1	hypothetical protein	-
KW2_RS11285 (kw2_2273)	hexA	2344480..2347002 (-)	2523	WP_021038001.1	DNA mismatch repair protein MutS	Machinery gene
KW2_RS11290 (kw2_2274)	-	2347118..2347465 (-)	348	WP_021038002.1	RicAFT regulatory complex protein RicA family protein	-
KW2_RS11295 (kw2_2275)	-	2347631..2348512 (-)	882	WP_021038003.1	NAD(P)-dependent oxidoreductase	-
KW2_RS11300 (kw2_2276)	-	2348555..2348761 (-)	207	WP_003132002.1	hypothetical protein	-
KW2_RS11310 (kw2_2278)	-	2349103..2349480 (-)	378	WP_011836124.1	DUF1634 domain-containing protein	-
KW2_RS11315 (kw2_2279)	-	2349480..2350331 (-)	852	WP_011836125.1	sulfite exporter TauE/SafE family protein	-
KW2_RS11320 (kw2_2280)	-	2350515..2350694 (+)	180	WP_011677262.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94300.30 Da
• Isoelectric Point: 4.6835

>NTDB_id=51702 KW2_RS11285 WP_021038001.1 2344480..2347002(-) (hexA) [Lactococcus cremoris subsp. cremoris KW2]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYEDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAATEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKAKRYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVVGFPLDEAQVKVFERQMNLLISEQFEIPENLLIELSGLTTLENQAASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQVFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILEVLDETPLNELRSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNVQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRAETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTEG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKATSRSLIIFDELGRGTATYDGMALAQAIIEYVHEHIGAKTLFATHYHELT
DLDKELDHLDNVHVATLEQNGNVTFLHKITDGPADKSYGIHVAKIAGLPQTLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFAENSSEIIEKIKGQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=51702 KW2_RS11285 WP_021038001.1 2344480..2347002(-) (hexA) [Lactococcus cremoris subsp. cremoris KW2]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAGGATTATCCCGATGCTTTTTTGCTCTTTCG
GATGGGTGATTTTTATGAACTTTTCTATGAGGATGCGGTAAATGCCGCTCAAATATTAGAGTTAACCCTGACTTCAAGAA
ACAAGAATTCCGAAAATCCAATTCCGATGGCTGGCGTGCCCCACCATGCGGCAACTGAATATATTGATAAATTGGTTGAC
TTAGGCTATAAAGTGGCAGTTGCTGAGCAAATGGAAGACCCGAAAAAAGCGGTAGGAATTGTCAAACGTGCCGTGACACA
AGTCATTACACCAGGAACGACAATTGATACTGCAAATTCAGTTGATAATAATTTCTTAGTAGCGATTGATTTTAAAGCTA
AACGTTATGCCCTCTCTTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCAGTCGTC
GGGGAAATTGCCTCGCTCAAAGCGCGTGAAATTGTTGTTGGTTTTCCTTTAGATGAGGCTCAAGTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAATTTGAGATTCCTGAAAATTTACTGATAGAATTATCAGGACTGACCACCTTAG
AAAATCAAGCCGCTTCAAAATTATTGGCTTATGTTAAAGAAACGCAAATGCGTGACTTGAGTCACTTACAAGAAGTTGAG
CACTATGAAATTAAAGATTTTTTGCAAATGGACTTTGCGACGAAATCTTCTTTAGAGCTGACAGCAAATAAAAGAGAAAA
CAAAAAACATGGGACCCTTTACTGGTTGCTTGATGAAACAAAAACAGCGATGGGGACGCGCATGTTACGTTCGTGGATTG
ACCGTCCTTTAGTTTCAAATTCAGCTATTCAAAAAAGAATGGAAATTGTCCAAGTTTTCTTAGACCATTTCTTTGAACGT
TCTGATTTAATAGAGGCTCTTAAAGGAGTTTACGATTTAGAACGTTTAGCTTCTCGGGTTTCTTTTGGTAAGGCTGTTCC
TGTTGATTTTTTGCAGCTGGCTAATTCCTTATCAAATGTTCCTGCCATCAAAAATATTTTGGAAGTTCTTGATGAAACGC
CCTTAAATGAGTTAAGAAGCCAATTGGATGAAATTCCGGAATTGTCTGGCTTGATTAATTCTGCCATTAGTGAAAATGCC
TCAAGAACGATTACCGAAGGGGGCATTATTAAAAAAGGCTATAATGTTCAATTAGATAAATATCGTGAGGCTCTTGAAAA
TGGAACTTCGTGGATTGCAAAATTGGAAGCAGATGAAAAAGCAAAAACAGGTATTTCTACACTGCGAATTGATTATAATC
GCAAGGATGGTTATTATTTCCATATCACCCAAAGTCAGTTGAATAGTGTACCTGAACATTTTTATCGTAAGGCAACTCTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTGACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCTTC
TCTGGAGTATGATTTATTCATGGGACTTCGGGCTGAAACAGAACAGTATATTGGCAGACTTCAAGCTCTAGCCAAAACTA
TTGCTGAAATTGACTGTCTGCAAAGTCTTTCTGTGGTTGCAGAAAAACAAGGATATATCCGTCCGACGCTTACAGAAGGC
TCAAGAATTGTTGAAATCAAAGGGGGACGTCATGCCGTAGTTGAAGCGGTCATGGGAGCTCAAGAATATGTCCCAAATGA
TATTGAACTGCCCGAACAAACTGATATTCAGCTCATCACAGGTCCGAATATGTCTGGGAAATCGACTTATATGCGTCAGT
TTGCGCTGACAGTGATTATGGCTCAGATTGGATCTTTTGTCCCAGCCGAAACAGCTAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCAACCTTTATGGTTGAGATGTCTGAGGCCAATCATGC
CATTCAAAAGGCGACAAGTCGCTCTTTGATTATCTTTGATGAGCTGGGGAGAGGAACGGCAACTTATGATGGGATGGCTC
TCGCTCAAGCGATTATTGAATATGTTCACGAACATATTGGAGCAAAAACACTTTTTGCTACTCATTATCATGAATTGACT
GATTTAGATAAAGAACTTGATCATTTAGATAATGTTCATGTTGCAACTTTGGAGCAAAATGGAAATGTAACCTTTTTACA
TAAGATTACAGATGGACCAGCCGATAAATCCTATGGGATTCATGTGGCAAAAATCGCTGGCCTGCCACAGACTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTACCAGCAAAAAAAGTTGCTGACGAACAAGAACAACTC
AGTTTATTTGATTTTGCTGAAAATTCGTCTGAAATTATTGAAAAAATAAAAGGACAGAATGTTGATAATATGACTGCAAG
AGAAGCCTTGAATTTCTTGTGGGAACTTAAAGATTCACTCTGA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain III (MutS_III) (254-544)

• MutS domain I (MutS_I) (7-116)

• MutS domain II (MutS_II) (124-237)

• MutS domain V (MutS_V) (598-784)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	65.166	100	0.655
mutS	Pseudomonas stutzeri strain ATCC 17587	38.201	100	0.389