Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   I6H78_RS07690 Genome accession   NZ_CP066059
Coordinates   1572664..1573326 (-) Length   220 a.a.
NCBI ID   WP_198459300.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1567664..1578326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS07660 (I6H78_07660) trpC 1567829..1568596 (+) 768 WP_198459295.1 indole-3-glycerol phosphate synthase TrpC -
  I6H78_RS07665 (I6H78_07665) - 1568583..1569182 (+) 600 WP_198459296.1 phosphoribosylanthranilate isomerase -
  I6H78_RS07670 (I6H78_07670) trpB 1569160..1570383 (+) 1224 WP_198459297.1 tryptophan synthase subunit beta -
  I6H78_RS07675 (I6H78_07675) trpA 1570376..1571152 (+) 777 WP_198459298.1 tryptophan synthase subunit alpha -
  I6H78_RS09485 - 1571124..1571210 (-) 87 Protein_1477 prepilin peptidase -
  I6H78_RS07680 (I6H78_07680) - 1571242..1572141 (-) 900 WP_000687279.1 helix-turn-helix transcriptional regulator -
  I6H78_RS07685 (I6H78_07685) - 1572220..1572675 (+) 456 WP_198459299.1 effector binding domain-containing protein -
  I6H78_RS07690 (I6H78_07690) cclA/cilC 1572664..1573326 (-) 663 WP_198459300.1 prepilin peptidase Machinery gene
  I6H78_RS07695 (I6H78_07695) - 1573396..1573851 (+) 456 WP_084849241.1 GNAT family N-acetyltransferase -
  I6H78_RS07700 (I6H78_07700) - 1573955..1574480 (+) 526 Protein_1482 thiol-disulfide isomerase -
  I6H78_RS07705 (I6H78_07705) - 1574551..1575072 (+) 522 WP_198459301.1 hypothetical protein -
  I6H78_RS07710 (I6H78_07710) - 1575295..1575498 (-) 204 WP_000102421.1 CsbD family protein -
  I6H78_RS07715 (I6H78_07715) - 1575540..1576124 (-) 585 WP_198459302.1 Asp23/Gls24 family envelope stress response protein -
  I6H78_RS07720 (I6H78_07720) - 1576136..1576306 (-) 171 WP_000454669.1 DUF2273 domain-containing protein -
  I6H78_RS07725 (I6H78_07725) amaP 1576318..1576881 (-) 564 WP_198459303.1 alkaline shock response membrane anchor protein AmaP -
  I6H78_RS07730 (I6H78_07730) - 1576981..1577217 (-) 237 WP_000964741.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25328.56 Da        Isoelectric Point: 7.8974

>NTDB_id=516990 I6H78_RS07690 WP_198459300.1 1572664..1573326(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_1021]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRFPFWYALFELGLG
LIFLSWSWDFLSLGQVILITAGLTLGIYDFRHQEYPLLVWLTFHLILMAFCGWNLVMLFFLALGIMAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLPQKKKERLPFVPFLLLAATIIIFYQFLLVC

Nucleotide


Download         Length: 663 bp        

>NTDB_id=516990 I6H78_RS07690 WP_198459300.1 1572664..1573326(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_1021]
ATGATTGATCTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTCGGTTTGGTCATTGACCGTTTCCCTGAGCA
ATCCATTATTCGACCAGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCGTTAGACCTAATTCCTATCCTCTCTC
AGGTCTTCAATCGCTTTCGCTGTCGCTATTGCAAGGTACGCTTTCCTTTCTGGTATGCCCTTTTTGAACTAGGCTTAGGG
CTCATCTTTCTGTCTTGGTCTTGGGACTTTCTTTCCTTGGGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCTTTACTAGTCTGGCTGACGTTCCACCTAATCCTCATGGCTTTCTGTGGTTGGA
ATCTGGTTATGCTCTTCTTCCTTGCCCTTGGAATCATGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCTCTCGTCTTTAGTGTGACCGAATTACTCATCTTGATTCAGTTTGCTTCTGCGACGGGGATCCT
AGCTTTTCTCCCGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTTGCTGCGACTATAATAATTTTCT
ATCAGTTCTTATTAGTTTGTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

89.041

99.545

0.886
  cclA/cilC Streptococcus pneumoniae Rx1

88.128

99.545

0.877
  cclA/cilC Streptococcus pneumoniae D39

88.128

99.545

0.877
  cclA/cilC Streptococcus pneumoniae R6

88.128

99.545

0.877
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

99.545

0.868
  cclA/cilC Streptococcus pneumoniae TIGR4

86.301

99.545

0.859