Detailed information NTG0516885

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: I6H72_RS08235
• Genome accession: NZ_CP066055
• Coordinates: 1636770..1637837 (+)
• Length: 355 a.a.
• NCBI ID: WP_006268109.1
• Uniprot ID: F9P7H5
• Organism: Streptococcus constellatus strain FDAARGOS_1015
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1631770..1642837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H72_RS08220 (I6H72_08220)	amiA3	1631996..1633975 (+)	1980	WP_198457823.1	peptide ABC transporter substrate-binding protein	Regulator
I6H72_RS08225 (I6H72_08225)	amiC	1634339..1635835 (+)	1497	WP_006268182.1	ABC transporter permease	Regulator
I6H72_RS08230 (I6H72_08230)	amiD	1635835..1636761 (+)	927	WP_198457824.1	oligopeptide ABC transporter permease OppC	Regulator
I6H72_RS08235 (I6H72_08235)	amiE	1636770..1637837 (+)	1068	WP_006268109.1	ABC transporter ATP-binding protein	Regulator
I6H72_RS08240 (I6H72_08240)	amiF	1637848..1638771 (+)	924	WP_198457825.1	ATP-binding cassette domain-containing protein	Regulator
I6H72_RS08245 (I6H72_08245)	-	1638914..1639738 (+)	825	Protein_1609	Cof-type HAD-IIB family hydrolase	-
I6H72_RS08250 (I6H72_08250)	-	1639808..1640773 (-)	966	WP_058669830.1	LacI family DNA-binding transcriptional regulator	-
I6H72_RS08255 (I6H72_08255)	-	1640754..1642208 (-)	1455	WP_198457826.1	sucrose-6-phosphate hydrolase	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39582.24 Da
• Isoelectric Point: 4.7899

>NTDB_id=516885 I6H72_RS08235 WP_006268109.1 1636770..1637837(+) (amiE) [Streptococcus constellatus strain FDAARGOS_1015]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEDNGRVAQGSINYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIVKHQKKTAKEAKEMAIDYMNKVGIPDAEKRFSEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQQEYQFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEDVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVSDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLDA

Nucleotide

• Length: 1068 bp

>NTDB_id=516885 I6H72_RS08235 WP_006268109.1 1636770..1637837(+) (amiE) [Streptococcus constellatus strain FDAARGOS_1015]
ATGACACAAGAAAAAAATGTAATATTGACTGCCCGCGATATTGTCGTGGAATTTGACGTTCGTGATAAAGTCTTAACCGC
CATTCGTGGTGTATCACTTGACCTCATCGAAGGTGAAGTTCTTGCTCTCGTAGGAGAGTCAGGTTCTGGTAAATCTGTTT
TAACAAAGACTTTTACTGGAATGTTAGAGGATAATGGTCGAGTAGCGCAAGGATCGATTAACTATCGTGGACAAGATTTG
ACAAAATTGAAATCCAATAAAGATTGGGAACCTATTCGTGGTGTTAAAATTGCGACTATTTTCCAAGACCCAATGACAAG
TTTAGACCCAATTAACACGATTGGTAGCCAGATTACAGAAGTTATTGTAAAACATCAAAAGAAAACGGCAAAAGAAGCGA
AGGAAATGGCTATTGACTATATGAATAAAGTCGGTATTCCTGATGCTGAAAAGCGTTTTAGTGAGTATCCTTTCCAATAT
TCAGGAGGAATGCGTCAACGGATCGTTATTGCCATTGCGCTTGCTTGTCGTCCTGATATCCTAATCTGTGATGAACCTAC
AACAGCGCTTGATGTTACCATTCAAGCACAAATCATTGATTTGTTGAAATCATTGCAACAAGAGTATCAATTCACTACTA
TTTTTATCACCCACGACCTTGGAGTGGTAGCAAGTATTGCGGATAAAGTTGCCGTTATGTATGCTGGAGAAATCGTCGAG
TATGGTACAGTAGAAGACGTCTTTTATGATCCACGTCATCCTTATACTTGGAGCTTGTTATCAAGCTTGCCACAGTTGGC
AGATGATAAAGGAGAGCTTTACTCTATTCCTGGCACACCGCCGTCTCTTTATTCACACTTGCAAGGAGATGCTTTCGCTC
TTCGTTCAGATTATGCGATGGAAATTGATTTTGAGGAAAAACCACCTCAAATCTATGTATCAGATACACATTGGGCAAAA
ACGTGGTTGCTTCATGAAAATGCTCCAAAAGTGAATAAACCTGCTGTTATTGATGATTTACATGAAAAAATTAGCTCAAA
AATGGGTTTTGCTCATTTAGACGCTTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9P7H5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.402	99.437	0.859
amiE	Streptococcus thermophilus LMG 18311	84.986	99.437	0.845
amiE	Streptococcus thermophilus LMD-9	84.986	99.437	0.845
oppD	Streptococcus mutans UA159	55.65	99.718	0.555