Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   I6H72_RS06375 Genome accession   NZ_CP066055
Coordinates   1270000..1271313 (+) Length   437 a.a.
NCBI ID   WP_232619560.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1265000..1276313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS06345 (I6H72_06345) dnaA 1265283..1266626 (-) 1344 WP_020997506.1 chromosomal replication initiator protein DnaA -
  I6H72_RS06350 (I6H72_06350) spo0J 1266855..1267622 (-) 768 WP_198457704.1 ParB/RepB/Spo0J family partition protein Regulator
  I6H72_RS06355 (I6H72_06355) htrA 1267677..1268867 (-) 1191 WP_198457705.1 S1C family serine protease Regulator
  I6H72_RS06360 (I6H72_06360) rlmH 1269072..1269551 (+) 480 WP_006268880.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6H72_RS06370 (I6H72_06370) - 1269834..1269980 (+) 147 WP_006268843.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I6H72_RS06375 (I6H72_06375) comD/comD1 1270000..1271313 (+) 1314 WP_232619560.1 GHKL domain-containing protein Regulator
  I6H72_RS06380 (I6H72_06380) comE 1271313..1272062 (+) 750 WP_003071650.1 competence system response regulator transcription factor ComE Regulator
  I6H72_RS06395 (I6H72_06395) - 1272383..1274959 (-) 2577 WP_198457706.1 YfhO family protein -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 51600.28 Da        Isoelectric Point: 7.4636

>NTDB_id=516864 I6H72_RS06375 WP_232619560.1 1270000..1271313(+) (comD/comD1) [Streptococcus constellatus strain FDAARGOS_1015]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFFKVKKHL
SVFLALFLSLAVSSSETFFSVIISSVTGDEFVDRYWGLFYIFINIISLIFILKTIDYFKFNFKYFKKVDFKDKIVQLNFY
LLFIHLLLNVSHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLYNEIR
GFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELTFEV
KDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRQLDLEMIYQIDFSTKGEGRGL
GLSNIKEIINNYEGIILDTNIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=516864 I6H72_RS06375 WP_232619560.1 1270000..1271313(+) (comD/comD1) [Streptococcus constellatus strain FDAARGOS_1015]
GTGAAAATAGAATTTATACATTGGATTATATTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGTTATAAGAAGATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAATAC
ATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAACATCTT
TCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTCTTCTGTCAC
AGGTGATGAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTTTTATTTTAAAAA
CTATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTTGATTTCAAAGATAAGATTGTACAATTAAATTTTTAT
CTATTATTTATTCATCTTTTATTAAATGTATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTTTTCTAGTATGAT
TGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGCGAAAAATATGAAAAAGAAGAAC
AAATTAAGCAAAAAGAACAGGAACAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTATAATGAAATTCGA
GGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAAAGAAGTGGAGCG
AATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATTTAAATAATGTTG
GAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTATTTAAGGCACGAGATTACAATATAGAATTAACATTTGAAGTA
AAAGATTTTGTCAAGCCTTTACCGATTAAATTATTAGATCTAGTTAGAATGACAAGTGTTCTTTTAAATAATGCCATAGA
AGGAGCAGCAGAAAGTTATCAAAAAACAATGAATGTTTCTTTGGTAGATTTGGATACAGAAACTATCTTAGTCATTCAAA
ATTCACGTAAAAAAAGACAACTAGACTTAGAAATGATTTATCAAATCGATTTTTCAACAAAGGGCGAGGGACGAGGTTTA
GGTTTAAGCAATATCAAAGAAATTATTAATAACTATGAAGGAATTATTCTTGATACAAACATTGAGGATGAATATTTTAC
ACAAGTAATGAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(330-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.795

100

0.549
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.549
  comD Streptococcus mitis SK321

46.939

89.703

0.421
  comD/comD2 Streptococcus pneumoniae TIGR4

48.138

86.041

0.414
  comD Streptococcus mitis NCTC 12261

48.138

86.041

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

47.606

86.041

0.41
  comD/comD1 Streptococcus pneumoniae D39

47.606

86.041

0.41
  comD/comD1 Streptococcus pneumoniae R6

47.606

86.041

0.41