Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   I6I32_RS07745 Genome accession   NZ_CP066041
Coordinates   1601453..1602115 (-) Length   220 a.a.
NCBI ID   WP_198464435.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1596453..1607115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS07715 (I6I32_07715) trpC 1596618..1597385 (+) 768 WP_198464433.1 indole-3-glycerol phosphate synthase TrpC -
  I6I32_RS07720 (I6I32_07720) - 1597372..1597971 (+) 600 WP_061427967.1 phosphoribosylanthranilate isomerase -
  I6I32_RS07725 (I6I32_07725) trpB 1597949..1599172 (+) 1224 WP_061427966.1 tryptophan synthase subunit beta -
  I6I32_RS07730 (I6I32_07730) trpA 1599165..1599941 (+) 777 WP_198464434.1 tryptophan synthase subunit alpha -
  I6I32_RS09670 - 1599913..1599999 (-) 87 Protein_1481 prepilin peptidase -
  I6I32_RS07735 (I6I32_07735) - 1600031..1600930 (-) 900 WP_000687279.1 helix-turn-helix transcriptional regulator -
  I6I32_RS07740 (I6I32_07740) - 1601009..1601464 (+) 456 WP_000682683.1 effector binding domain-containing protein -
  I6I32_RS07745 (I6I32_07745) cclA/cilC 1601453..1602115 (-) 663 WP_198464435.1 prepilin peptidase Machinery gene
  I6I32_RS07750 (I6I32_07750) - 1602185..1602640 (+) 456 WP_198464436.1 GNAT family N-acetyltransferase -
  I6I32_RS07755 (I6I32_07755) - 1602744..1603267 (+) 524 Protein_1486 thiol-disulfide isomerase -
  I6I32_RS07760 (I6I32_07760) - 1603338..1603859 (+) 522 WP_198464437.1 hypothetical protein -
  I6I32_RS07765 (I6I32_07765) - 1604077..1604280 (-) 204 WP_000102421.1 CsbD family protein -
  I6I32_RS07770 (I6I32_07770) - 1604322..1604906 (-) 585 WP_084849238.1 Asp23/Gls24 family envelope stress response protein -
  I6I32_RS07775 (I6I32_07775) - 1604918..1605088 (-) 171 WP_198464438.1 DUF2273 domain-containing protein -
  I6I32_RS07780 (I6I32_07780) amaP 1605100..1605663 (-) 564 WP_000045613.1 alkaline shock response membrane anchor protein AmaP -
  I6I32_RS07785 (I6I32_07785) - 1605763..1605999 (-) 237 WP_000964741.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25233.50 Da        Isoelectric Point: 7.9063

>NTDB_id=516679 I6I32_RS07745 WP_198464435.1 1601453..1602115(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_1075]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPLDLIPILSQLFNRFRCRYCKAHYPFWYALFELGLG
LLFLTWSLGWISLGQVILITAGLTLGIYDFRHQEYPLLVWLTFHLILMAFCGWNLVMVFFLILGIMAHFIDIRMGAGDFL
FLASCALIFSATELLILIQFASAAGILAFLLQKKKERLPFVPFLLLAATIIIFYQFLLVC

Nucleotide


Download         Length: 663 bp        

>NTDB_id=516679 I6I32_RS07745 WP_198464435.1 1601453..1602115(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_1075]
ATGATTGATCTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCTTTCTTGGGTTTGGTCATTGACCGTTTCCCTGAGCA
ATCCATTATACGCCCGGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCGTTAGACCTAATTCCTATCCTCTCTC
AGCTCTTCAATCGCTTTCGCTGTCGCTATTGTAAGGCTCACTATCCATTCTGGTATGCCCTCTTTGAACTCGGCTTAGGA
CTCCTCTTTCTGACTTGGTCTTTGGGTTGGATTTCCTTGGGTCAAGTCATCCTCATCACTGCTGGCTTGACCTTGGGAAT
CTATGACTTTCGCCATCAGGAATATCCCTTGCTGGTCTGGCTGACTTTCCACCTAATCCTCATGGCTTTCTGTGGTTGGA
ATCTAGTCATGGTCTTCTTCCTTATACTTGGAATCATGGCCCATTTTATCGATATTCGCATGGGCGCAGGGGATTTTCTC
TTTCTAGCTTCTTGTGCTCTCATCTTTAGCGCGACAGAATTACTCATCTTGATTCAGTTCGCTTCTGCGGCAGGCATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCGACTATAATAATTTTCT
ATCAGTTCTTATTAGTTTGTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

88.584

99.545

0.882
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

99.545

0.864
  cclA/cilC Streptococcus pneumoniae Rx1

86.758

99.545

0.864
  cclA/cilC Streptococcus pneumoniae D39

86.758

99.545

0.864
  cclA/cilC Streptococcus pneumoniae R6

86.758

99.545

0.864
  cclA/cilC Streptococcus pneumoniae TIGR4

85.845

99.545

0.855