Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6I32_RS05585 Genome accession   NZ_CP066041
Coordinates   1135988..1137286 (+) Length   432 a.a.
NCBI ID   WP_198464246.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1130988..1142286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS05560 (I6I32_05560) rpsB 1131813..1132592 (+) 780 WP_000268475.1 30S ribosomal protein S2 -
  I6I32_RS05565 (I6I32_05565) tsf 1132671..1133711 (+) 1041 WP_000808059.1 translation elongation factor Ts -
  I6I32_RS05570 (I6I32_05570) cysK 1133814..1134740 (-) 927 WP_198464244.1 cysteine synthase A -
  I6I32_RS05575 (I6I32_05575) - 1134837..1135280 (-) 444 WP_033584681.1 PH domain-containing protein -
  I6I32_RS05580 (I6I32_05580) - 1135296..1135931 (-) 636 WP_198464245.1 YigZ family protein -
  I6I32_RS05585 (I6I32_05585) comFA/cflA 1135988..1137286 (+) 1299 WP_198464246.1 DEAD/DEAH box helicase Machinery gene
  I6I32_RS05590 (I6I32_05590) comFC/cflB 1137283..1137945 (+) 663 WP_198464247.1 ComF family protein Machinery gene
  I6I32_RS05595 (I6I32_05595) hpf 1138025..1138573 (+) 549 WP_000599111.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6I32_RS05600 (I6I32_05600) - 1138655..1139833 (+) 1179 WP_198464248.1 acetyl-CoA C-acetyltransferase -
  I6I32_RS05605 (I6I32_05605) - 1139990..1141963 (+) 1974 WP_198464249.1 DHH family phosphoesterase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49665.64 Da        Isoelectric Point: 8.6628

>NTDB_id=516663 I6I32_RS05585 WP_198464246.1 1135988..1137286(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1075]
MKVNPNYLGRLFTEKELTEEERQVAVKLPAMRKEKGKLFCQRCNSSILEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
ENFPKQDVLKWRGQLTPFQEKVSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVIATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRIFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LQVHFPDENIGFVSSITEDRLEQVQAFRDGERTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=516663 I6I32_RS05585 WP_198464246.1 1135988..1137286(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAAGAACGACAGGTTGCAGTGAA
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTTCGATTCTAGAAGAATGGTATTTGC
CTATTGGCGCCTACTATTGCAGGGAGTGCTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCACAG
GAGAATTTTCCTAAGCAAGATGTTCTCAAATGGCGTGGTCAGTTAACCCCTTTTCAGGAAAAGGTATCAGAGGGGTTGAT
TCGAGCAGTCGAAAAGAAAGAACCGACTTTAGTTCATGCTGTGACAGGAGCTGGAAAGACAGAGATGATTTATCAAGTTG
TGGCCAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATTGATGTATGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCCTAGTAATTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATATTCCTTACGGCAACTTCTACA
GATGAATTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATA
CTACAGGTGCATTTCCCAGATGAGAATATCGGTTTTGTATCTTCTATCACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACGAACAATACTGATCAGTACGACAATATTGGAACGCGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGACTCTTTACCAAGTCTAGTTTGATTCAGATTGGTGGGCGAGTTGGGCGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGACTAAATGCTTCCATCAAGAAGGCAATCAAGGAAATCAAGCAGATGAA
CAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.278

100

0.903
  comFA/cflA Streptococcus mitis SK321

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae Rx1

89.352

100

0.894
  comFA/cflA Streptococcus pneumoniae D39

89.352

100

0.894
  comFA/cflA Streptococcus pneumoniae R6

89.352

100

0.894
  comFA/cflA Streptococcus pneumoniae TIGR4

89.12

100

0.891
  comFA Lactococcus lactis subsp. cremoris KW2

50.856

94.676

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

39.408

100

0.4
  comFA Bacillus subtilis subsp. subtilis str. 168

39.152

92.824

0.363