Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6H76_RS08605 Genome accession   NZ_CP065994
Coordinates   1672475..1673827 (+) Length   450 a.a.
NCBI ID   WP_006532761.1    Uniprot ID   A0A380KNR2
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1667475..1678827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS08575 (I6H76_08575) - 1667846..1668454 (+) 609 WP_006532767.1 TVP38/TMEM64 family protein -
  I6H76_RS08580 (I6H76_08580) - 1668492..1669139 (-) 648 WP_006532766.1 amino acid ABC transporter permease -
  I6H76_RS08585 (I6H76_08585) - 1669152..1669856 (-) 705 WP_006532765.1 amino acid ABC transporter permease -
  I6H76_RS08590 (I6H76_08590) - 1669873..1670685 (-) 813 WP_043878445.1 transporter substrate-binding domain-containing protein -
  I6H76_RS08595 (I6H76_08595) - 1670696..1671460 (-) 765 WP_006532763.1 amino acid ABC transporter ATP-binding protein -
  I6H76_RS08600 (I6H76_08600) vicR 1671772..1672482 (+) 711 WP_006532762.1 response regulator YycF Regulator
  I6H76_RS08605 (I6H76_08605) vicK 1672475..1673827 (+) 1353 WP_006532761.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6H76_RS08610 (I6H76_08610) vicX 1673828..1674637 (+) 810 WP_006532760.1 MBL fold metallo-hydrolase Regulator
  I6H76_RS08615 (I6H76_08615) rnc 1674859..1675545 (+) 687 WP_006532759.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51307.26 Da        Isoelectric Point: 4.6914

>NTDB_id=516154 I6H76_RS08605 WP_006532761.1 1672475..1673827(+) (vicK) [Streptococcus infantarius strain FDAARGOS_1019]
MNDTMVQNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDCERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRIIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=516154 I6H76_RS08605 WP_006532761.1 1672475..1673827(+) (vicK) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAATGATACAATGGTACAGAATCAATATCTGTTTGAACAAGCCATTCTTTTCTTGTTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGTCGATTGAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGATAGAGATTTAGCAGAGCTGGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTGGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTAGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGAATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTATCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGTGATGAGACGGGAGAATTTATCACTTTGCGCATTCGATTCGCCTTAAATCGTAGAGATAGTGG
TTTTATTTCTGGGCTGATTGCTGTCTTGCATGATACGACAGAGCAAGAAAAAGAAGACTGTGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCACGAGTTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAGGCACTGGATGAAGGGGCTCTGAAA
GAAGATATTGCACCAAGTTTCATTAAAGTTTCTTTGGATGAAACCAATCGTATAATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACGAATTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAAAGTCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCGATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACCCAGGTCTTGGATAATATTCTAAATAATGCCATTAAGTATTCACCAGA
CGGTGGTAAGATCACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KNR2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.386

92.222

0.704
  micB Streptococcus pneumoniae Cp1015

63.781

97.556

0.622