Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6H76_RS07875 Genome accession   NZ_CP065994
Coordinates   1533147..1533839 (+) Length   230 a.a.
NCBI ID   WP_006532917.1    Uniprot ID   A0A380KNN3
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1528147..1538839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS07850 (I6H76_07850) - 1528224..1529597 (-) 1374 WP_043878458.1 TrkH family potassium uptake protein -
  I6H76_RS07855 (I6H76_07855) rsmG 1529662..1530375 (-) 714 WP_006532921.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  I6H76_RS07860 (I6H76_07860) - 1530665..1531216 (+) 552 WP_014335211.1 LemA family protein -
  I6H76_RS07865 (I6H76_07865) htpX 1531329..1532228 (+) 900 WP_006532919.1 zinc metalloprotease HtpX -
  I6H76_RS07870 (I6H76_07870) - 1532370..1532906 (+) 537 WP_043878457.1 DUF177 domain-containing protein -
  I6H76_RS07875 (I6H76_07875) covR 1533147..1533839 (+) 693 WP_006532917.1 response regulator transcription factor Regulator
  I6H76_RS07880 (I6H76_07880) - 1533839..1535308 (+) 1470 WP_006532916.1 ATP-binding protein -
  I6H76_RS07885 (I6H76_07885) nrdR 1535490..1535984 (+) 495 WP_006532915.1 transcriptional regulator NrdR -
  I6H76_RS07890 (I6H76_07890) - 1535971..1537122 (+) 1152 WP_006532914.1 DnaD domain protein -
  I6H76_RS07895 (I6H76_07895) dnaI 1537133..1538035 (+) 903 WP_006532913.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26400.31 Da        Isoelectric Point: 4.7654

>NTDB_id=516150 I6H76_RS07875 WP_006532917.1 1533147..1533839(+) (covR) [Streptococcus infantarius strain FDAARGOS_1019]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=516150 I6H76_RS07875 WP_006532917.1 1533147..1533839(+) (covR) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACTGCATTGGATGATGATTTTGATTTGATCCTATTGGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGACACATCAATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTCGACCGTGGCGCAGATGATTATATTGTAAAACCATTTGCTATTGA
AGAATTACTTGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGACAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCTGCAGTTCGTGGTGATGATGAAATTTCATTAACAAAACGT
GAATACGATTTGTTGAGCGTGCTTCTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATCGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KNN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.087

100

0.761
  covR Lactococcus lactis subsp. lactis strain DGCC12653

64.192

99.565

0.639
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417
  vicR Streptococcus mutans UA159

41.558

100

0.417