Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STMM8_RS01640 Genome accession   NZ_CP065787
Coordinates   295394..296083 (+) Length   229 a.a.
NCBI ID   WP_022096581.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 290394..301083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM8_RS01620 (STMM8_01620) - 291547..292218 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STMM8_RS01625 (STMM8_01625) - 292258..293622 (-) 1365 WP_002946491.1 TrkH family potassium uptake protein -
  STMM8_RS01630 (STMM8_01630) rsmG 293692..294405 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STMM8_RS01635 (STMM8_01635) - 294702..295238 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  STMM8_RS01640 (STMM8_01640) covR 295394..296083 (+) 690 WP_022096581.1 response regulator transcription factor Regulator
  STMM8_RS01645 (STMM8_01645) covS 296080..297597 (+) 1518 WP_022096582.1 HAMP domain-containing histidine kinase Regulator
  STMM8_RS01650 (STMM8_01650) nrdR 297719..298198 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STMM8_RS01655 (STMM8_01655) - 298195..299370 (+) 1176 WP_002949643.1 DnaD domain protein -
  STMM8_RS01660 (STMM8_01660) dnaI 299374..300276 (+) 903 WP_002946786.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26623.71 Da        Isoelectric Point: 4.7059

>NTDB_id=514248 STMM8_RS01640 WP_022096581.1 295394..296083(+) (covR) [Streptococcus thermophilus strain MM8]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLVLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=514248 STMM8_RS01640 WP_022096581.1 295394..296083(+) (covR) [Streptococcus thermophilus strain MM8]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTGTGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTTCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

44.828

100

0.454
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437