Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   I6G42_RS04995 Genome accession   NZ_CP065707
Coordinates   1023410..1024069 (-) Length   219 a.a.
NCBI ID   WP_038804948.1    Uniprot ID   A0A7T3DY88
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1018410..1029069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS04965 (I6G42_04965) - 1018537..1019103 (+) 567 WP_038804943.1 aminodeoxychorismate/anthranilate synthase component II -
  I6G42_RS04970 (I6G42_04970) trpD 1019114..1020118 (+) 1005 WP_038804944.1 anthranilate phosphoribosyltransferase -
  I6G42_RS04975 (I6G42_04975) trpC 1020115..1020882 (+) 768 WP_038804945.1 indole-3-glycerol phosphate synthase TrpC -
  I6G42_RS04980 (I6G42_04980) - 1020869..1021468 (+) 600 WP_038804946.1 phosphoribosylanthranilate isomerase -
  I6G42_RS04985 (I6G42_04985) trpB 1021446..1022669 (+) 1224 WP_000331265.1 tryptophan synthase subunit beta -
  I6G42_RS04990 (I6G42_04990) trpA 1022662..1023438 (+) 777 WP_038804947.1 tryptophan synthase subunit alpha -
  I6G42_RS04995 (I6G42_04995) cclA/cilC 1023410..1024069 (-) 660 WP_038804948.1 prepilin peptidase Machinery gene
  I6G42_RS05000 (I6G42_05000) - 1024139..1024594 (+) 456 WP_038804949.1 GNAT family N-acetyltransferase -
  I6G42_RS05005 (I6G42_05005) - 1024964..1026109 (-) 1146 WP_038804950.1 low temperature requirement protein A -
  I6G42_RS05010 (I6G42_05010) - 1026915..1028204 (+) 1290 WP_038804951.1 membrane protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24947.30 Da        Isoelectric Point: 8.6809

>NTDB_id=513302 I6G42_RS04995 WP_038804948.1 1023410..1024069(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_885]
MIDLYFFLVGNILASFLGLVIDRFPDQSIIRPASHCNSCQTRLRPLDLIPILSQVFNRFRCRYCKIRYPIWYALFELGLG
LVFLAWSWGCISIGQVILITAGLTLGIYDFRHQEYPLLVWLTFHLIILAFCGWNLVMVFFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLKKKKERLPFVPFLLLAACMIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=513302 I6G42_RS04995 WP_038804948.1 1023410..1024069(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_885]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAACATTCTCGCTTCCTTTCTAGGTTTGGTCATTGACCGTTTCCCTGACCA
ATCCATTATTCGACCAGCTAGCCACTGCAATTCCTGTCAGACTCGCTTGCGTCCGCTAGATTTGATTCCTATCCTTTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGATTCGCTATCCAATCTGGTATGCTCTCTTTGAACTCGGCTTAGGG
CTTGTCTTTCTGGCTTGGTCTTGGGGCTGTATTTCCATAGGACAAGTCATCCTCATCACTGCTGGCTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCCTACTGGTCTGGCTGACTTTTCACCTAATCATCCTGGCTTTCTGTGGTTGGA
ATCTGGTCATGGTCTTCTTTCTTGCCCTTGGAATTTTGGCGCATTTTATCGATATTCGCATGGGTGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCTCTCGTCTTTAGTGTGACCGAACTACTCATCTTGATTCAGTTCGCTTCTGCAACAGGAATTCT
AGCCTTTCTCCTGAAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGCATGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DY88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

88.584

100

0.886
  cclA/cilC Streptococcus pneumoniae Rx1

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae D39

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae R6

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae TIGR4

86.758

100

0.868
  cclA/cilC Streptococcus mitis NCTC 12261

86.301

100

0.863