Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   I6G42_RS00125 Genome accession   NZ_CP065707
Coordinates   16961..17698 (-) Length   245 a.a.
NCBI ID   WP_038804519.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 11961..22698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS00110 (I6G42_00110) - 13991..15352 (+) 1362 WP_038804515.1 bacteriocin secretion accessory protein -
  I6G42_RS00115 (I6G42_00115) blpC 15409..15564 (+) 156 WP_038804516.1 quorum-sensing system pheromone BlpC -
  I6G42_RS00120 (I6G42_00120) - 15607..16947 (-) 1341 WP_038804518.1 sensor histidine kinase -
  I6G42_RS00125 (I6G42_00125) comE/blpR 16961..17698 (-) 738 WP_038804519.1 response regulator transcription factor Regulator
  I6G42_RS00130 (I6G42_00130) - 17703..18041 (-) 339 WP_038804520.1 LytTR family DNA-binding domain-containing protein -
  I6G42_RS00135 (I6G42_00135) - 18320..18649 (+) 330 WP_038804521.1 hypothetical protein -
  I6G42_RS00140 (I6G42_00140) - 18814..19863 (-) 1050 WP_038804522.1 ABC transporter permease -
  I6G42_RS00145 (I6G42_00145) pptA 19860..20591 (-) 732 WP_038804523.1 ABC transporter ATP-binding protein Regulator
  I6G42_RS00150 (I6G42_00150) - 20659..21069 (+) 411 WP_038804524.1 HIT family protein -
  I6G42_RS00155 (I6G42_00155) - 21079..21357 (+) 279 WP_000777742.1 hypothetical protein -
  I6G42_RS00160 (I6G42_00160) - 21421..22080 (+) 660 WP_038804526.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28813.97 Da        Isoelectric Point: 6.0460

>NTDB_id=513249 I6G42_RS00125 WP_038804519.1 16961..17698(-) (comE/blpR) [Streptococcus oralis strain FDAARGOS_885]
MRIFVLEDDFSQQTRIETTIEKLLKEHHIIPSSFEVFGKPDQLLAEMHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKSLSAEEFESRIETALLYADSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=513249 I6G42_RS00125 WP_038804519.1 16961..17698(-) (comE/blpR) [Streptococcus oralis strain FDAARGOS_885]
ATGAGAATATTTGTTTTAGAAGATGATTTCTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAAGAACA
TCATATCATTCCCAGCTCTTTTGAAGTCTTTGGCAAGCCAGACCAACTTCTGGCAGAGATGCATGAGAAGGGAGCACATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAAGGCCTAGAAGTGGCAAGAAAGATTCGGGATCGAGAT
CCTTATGCCCTGATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGTCCTTGTCGGCGGAGGAGTTTGAGTCTCGTATCGAGACAGCTCTTCTCTATGCCGATAGTCAAGACA
GCAAAAGCCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCTCCTAGAGCCCATCGTGTTATTCTCTATACCAAGACGGATAGACTGGAATTTACGGCGAGCCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGTCATCGTTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTTAGGGAAGTTTCTGAGGCT
ATCAATAATTTGCATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.132

98.776

0.535
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38
  comE Streptococcus infantis strain Atu-4

36.179

100

0.363