Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6G43_RS04505 Genome accession   NZ_CP065706
Coordinates   948219..949556 (+) Length   445 a.a.
NCBI ID   WP_009014020.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 943219..954556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS04485 (I6G43_04485) - 943491..944339 (+) 849 WP_038806193.1 putative PEP-binding protein -
  I6G43_RS04490 (I6G43_04490) - 944336..944776 (+) 441 WP_038806192.1 ASCH domain-containing protein -
  I6G43_RS04495 (I6G43_04495) - 944897..947443 (+) 2547 WP_038806191.1 M1 family metallopeptidase -
  I6G43_RS04500 (I6G43_04500) ciaR 947555..948229 (+) 675 WP_000590635.1 two-component system response regulator CiaR Regulator
  I6G43_RS04505 (I6G43_04505) ciaH 948219..949556 (+) 1338 WP_009014020.1 sensor histidine kinase Regulator
  I6G43_RS04510 (I6G43_04510) - 949624..949908 (-) 285 WP_001111510.1 DUF3270 domain-containing protein -
  I6G43_RS04515 (I6G43_04515) - 950293..951348 (+) 1056 WP_000280273.1 ABC transporter permease -
  I6G43_RS04520 (I6G43_04520) - 951362..952042 (+) 681 WP_000125742.1 ABC transporter ATP-binding protein -
  I6G43_RS04525 (I6G43_04525) - 952170..953099 (+) 930 WP_038806190.1 peptidase U32 family protein -
  I6G43_RS04530 (I6G43_04530) rpiA 953205..953888 (+) 684 WP_038806189.1 ribose-5-phosphate isomerase RpiA -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 50870.57 Da        Isoelectric Point: 9.5658

>NTDB_id=513220 I6G43_RS04505 WP_009014020.1 948219..949556(+) (ciaH) [Streptococcus oralis strain FDAARGOS_886]
MFNKLRKTWYADDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLQALSSSPQAVIQLALNRATEEVKDIQPAT
ADASKAEIKPNVSSNTEVLLFDKDFNQLLLGNRFLGLDKIKLDKKELNHIRQIQVVNSYGQEETYRMILMETNSSTVSSN
VKYAAVLINTSQLEQISQNHEHLIVVVMASFWLLSLIASVYLARVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLE
NLFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEIAEVSPQFFKTTFANYELIASENDRVFEYENRI
YRPFMTDQLLLKQLMTILFDNAIKYTEEDGKIEFVVYATDRHLYLTVTDNGIGISAPDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALRGTISVKDNKPRGTIFEVKIAIQSPSKRKNK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=513220 I6G43_RS04505 WP_009014020.1 948219..949556(+) (ciaH) [Streptococcus oralis strain FDAARGOS_886]
ATGTTCAATAAACTAAGAAAAACATGGTATGCGGATGATTTCAGCTATTTCATTCGAAACTTTGGAGTGTTCACCCTGAT
CTTCTCTGCCATGACCTTGATTATCCTCCAGGTCATGCACTCGAGTCTCTACACTTCTGTAGATGAAAAACTCCAAGCCC
TTAGTAGTAGTCCCCAAGCGGTTATCCAGTTAGCCCTGAATCGGGCAACTGAGGAAGTCAAAGATATTCAACCAGCAACA
GCGGATGCCAGCAAGGCTGAAATCAAACCCAATGTCAGCTCCAATACGGAAGTCTTGCTCTTTGACAAGGATTTTAACCA
ACTCTTACTGGGCAATCGTTTTTTAGGCTTGGACAAGATCAAGCTGGACAAAAAAGAGTTGAATCACATTCGGCAAATCC
AAGTTGTCAATAGCTACGGTCAGGAAGAAACCTACCGAATGATCTTGATGGAAACAAATTCGTCCACTGTTTCAAGCAAT
GTCAAATATGCGGCGGTTTTAATCAATACCAGCCAGCTCGAGCAAATCAGCCAAAACCACGAGCATTTAATTGTTGTAGT
CATGGCTAGTTTCTGGCTCCTGTCTTTAATTGCCAGTGTTTACTTGGCACGTGTCAGTGTCAAACCCTTGCTGGAAAGTA
TGCAAAAGCAGAAGTCCTTTGTTGAAAATGCCAGTCATGAACTGAGAACGCCTTTGGCCGTTTTACAAAATCGTTTAGAA
AATCTTTTTCGAAAACCAGAGGCAACGATTATGGAATCCAGCGAAAGCATCGCTTCGAGTCTTGAAGAAGTTCGCAACAT
GCGCTTCCTTACAACTAATCTTCTCAACCTTGCACGTCGAGATGATGGAATCAAGCCAGAAATAGCAGAAGTATCACCAC
AGTTCTTTAAGACGACCTTTGCTAACTATGAGTTGATTGCTTCTGAAAATGATCGTGTTTTTGAGTATGAAAATCGGATT
TATCGCCCATTCATGACCGATCAGTTGCTCCTAAAACAGCTCATGACTATCTTATTTGATAATGCCATCAAGTATACCGA
AGAAGATGGGAAAATTGAGTTTGTGGTTTATGCTACAGATCGCCACCTCTATCTAACAGTAACGGATAATGGAATTGGAA
TCTCAGCTCCTGACAAGAAGAAAATCTTTGACCGATTTTACCGTGTAGACAAGGCGAGAACTCGTCAGAAAGGCGGTTTC
GGTCTGGGCCTATCTTTGGCCAAGCAGATTGTAGATGCCTTACGAGGAACGATTAGCGTCAAAGATAACAAGCCTAGAGG
AACAATTTTTGAAGTTAAAATCGCAATTCAATCTCCTTCAAAACGTAAGAATAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae D39

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae R6

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae TIGR4

83.973

99.551

0.836
  ciaH Streptococcus mutans UA159

55.251

98.427

0.544