Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   I6G43_RS03440 Genome accession   NZ_CP065706
Coordinates   734305..734964 (-) Length   219 a.a.
NCBI ID   WP_038806290.1    Uniprot ID   A0A7T2ZPH3
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 729305..739964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS03410 (I6G43_03410) - 729432..729998 (+) 567 WP_000601900.1 aminodeoxychorismate/anthranilate synthase component II -
  I6G43_RS03415 (I6G43_03415) trpD 730009..731013 (+) 1005 WP_000658674.1 anthranilate phosphoribosyltransferase -
  I6G43_RS03420 (I6G43_03420) trpC 731010..731777 (+) 768 WP_038806294.1 indole-3-glycerol phosphate synthase TrpC -
  I6G43_RS03425 (I6G43_03425) - 731764..732363 (+) 600 WP_038806293.1 phosphoribosylanthranilate isomerase -
  I6G43_RS03430 (I6G43_03430) trpB 732341..733564 (+) 1224 WP_038806292.1 tryptophan synthase subunit beta -
  I6G43_RS03435 (I6G43_03435) trpA 733557..734333 (+) 777 WP_038806291.1 tryptophan synthase subunit alpha -
  I6G43_RS03440 (I6G43_03440) cclA/cilC 734305..734964 (-) 660 WP_038806290.1 prepilin peptidase Machinery gene
  I6G43_RS03445 (I6G43_03445) - 735034..735489 (+) 456 WP_038806289.1 GNAT family N-acetyltransferase -
  I6G43_RS03450 (I6G43_03450) - 735569..736828 (+) 1260 WP_038806468.1 S41 family peptidase -
  I6G43_RS03455 (I6G43_03455) - 737349..738494 (-) 1146 WP_038806288.1 low temperature requirement protein A -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24975.16 Da        Isoelectric Point: 7.6418

>NTDB_id=513215 I6G43_RS03440 WP_038806290.1 734305..734964(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_886]
MIDFYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALLELGLG
LLFLAWSWELLSLSQVILITAGLTLGIYDFHHQEYPLLVWMTFHLILMASYGWNLVMVFFLALGILAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=513215 I6G43_RS03440 WP_038806290.1 734305..734964(-) (cclA/cilC) [Streptococcus oralis strain FDAARGOS_886]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCTGAGCA
ATCCATTATCCGCCCGGCTAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCGC
AGGTCTTTAATCGCTTTCGCTGTCGCTACTGCAAGGTTCGCTATCCTGTCTGGTATGCCCTTTTGGAACTAGGCTTAGGG
CTCCTCTTTCTGGCTTGGTCTTGGGAATTGCTTTCCTTGAGTCAAGTCATCCTCATAACTGCTGGCTTGACCTTGGGCAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGCTTCCTATGGCTGGA
ATCTAGTCATGGTCTTCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTTCTC
TTTTTAGCTTCCTGCGCTCTCGTCTTTAGTGCGACTGAACTACTGATCTTGATTCAGTTCGCTTCTGCGACAGGAATTCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

93.607

100

0.936
  cclA/cilC Streptococcus pneumoniae Rx1

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae D39

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae R6

93.151

100

0.932
  cclA/cilC Streptococcus pneumoniae TIGR4

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

88.584

100

0.886